Biomaterials as Stem Cell Niche

  • Krishnendu Roy

Part of the Studies in Mechanobiology, Tissue Engineering and Biomaterials book series (SMTEB, volume 2)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Sarah E. Stabenfeldt, Ashley Carson Brown, Thomas H. Barker
    Pages 1-18
  3. Ameya Phadke, Chien-Wen Chang, Shyni Varghese
    Pages 19-44
  4. Andres Bratt-Leal, Richard Carpenedo, Todd McDevitt
    Pages 45-59
  5. Benjamin K. K. Teo, Soneela Ankam, Evelyn K. F. Yim
    Pages 61-87
  6. Hai-Quan Mao, Shawn H. Lim, Shuming Zhang, Gregory Christopherson, Korey Kam, Stephen Fischer
    Pages 89-118
  7. Sharon K. Hamilton, Hang Lu, Johnna S. Temenoff
    Pages 119-152
  8. Hojae Bae, Jason W. Nichol, Amir Foudeh, Behnam Zamanian, Cheong Hoon Kwon, Ali Khademhosseini
    Pages 153-171
  9. Ge Zhang, Laura J. Suggs
    Pages 173-193
  10. Guoming Sun, Sravanti Kusuma, Sharon Gerecht
    Pages 195-223
  11. Ankur Singh, Krishnendu Roy
    Pages 225-245
  12. Back Matter
    Pages 309-309

About this book


Recent developments in stem cell biology have opened new directions in cell therapy. This book provides the state-of-the-art developments in using biomaterials as artificial niches for engineering stem cells, both for the purpose of better understanding their biology under 3D biomimetic conditions as well as for developing new strategies for efficient long term maintenance and directed differentiation of stem cells into various therapeutic lineages. Animal and human stem cells of both embryonic and adult origin are discussed with applications ranging from nerve regeneration, orthopedics, cardiovascular therapy, blood cell generation and cancer therapy. Both synthetic and natural biomaterials are reviewed with emphasis on how material-stem cell interactions direct specific signaling pathways and ultimately modulate the cell fate. This book is valuable for biomaterial scientists, tissue engineers, clinicians as well as stem cell biologists involved in basic research and applications of adult and embryonic stem cells.


Biomaterials Cell Differentiation Cell Signaling Regenerative Medicine Scaffolds Stem Cells Tissue Engineering

Editors and affiliations

  • Krishnendu Roy
    • 1
  1. 1.Cockrell School of Engineering, Dept. Biomedical EngineeringUniversity of Texas, AustinAustinUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2010
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Engineering
  • Print ISBN 978-3-642-13892-8
  • Online ISBN 978-3-642-13893-5
  • Series Print ISSN 1868-2006
  • Series Online ISSN 1868-2014
  • Buy this book on publisher's site