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Genetic Disorders Among Arab Populations

  • Ahmad S. Teebi

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Introduction

    1. Front Matter
      Pages 1-1
  3. Demography, Economy, and Genetic Services in Arab Countries

    1. Front Matter
      Pages 35-35
    2. Sulayman S. Al-Qudsi
      Pages 37-63
    3. Alan H. Bittles, Hanan A. Hamamy
      Pages 85-108
  4. Selected Disease Entities Prevalent Among the Arabs

    1. Front Matter
      Pages 109-109
    2. Hatem El-Shanti, Hasan Abdel Majeed
      Pages 111-143
    3. Ahmad S. Teebi
      Pages 181-216
  5. Genetic disorders in Arab Countries & Geographic Regions

    1. Front Matter
      Pages 217-217
    2. Samia A. Temtamy, Mona S. Aglan, Nagwa A. Meguid
      Pages 219-272
    3. Chahira Kozma
      Pages 273-295
    4. Hanan Ali Hamamy
      Pages 297-323
    5. Majed Dasouki, Hatem El-Shanti
      Pages 325-352
    6. Nawal Makhseed
      Pages 353-375
    7. Vazken M. Der Kaloustian
      Pages 377-441
    8. Tawfeg Ben-Omran
      Pages 443-454
    9. Abdelaziz Sefiani
      Pages 455-472
    10. Anna Rajab
      Pages 473-490
    11. Bassam Abu-Libdeh, Ahmad Said Teebi
      Pages 491-514
    12. Ahmad S. Teebi, Tawfeg Ben-Omran
      Pages 515-530
    13. Zuhair N. Al-Hassnan, Nadia Sakati
      Pages 531-573
    14. Mustafa A. M. Salih
      Pages 575-612
    15. Elham Hassen, Lotfi Chouchane
      Pages 613-638
    16. Lihadh Al-Gazali, Bassam R. Ali
      Pages 639-676
    17. Efrat Dagan, Ruth Gershoni-Baruch
      Pages 677-702
  6. Cultural and Religious Attitudes Towards Genetic Issues

    1. Front Matter
      Pages 703-703
    2. Shelley J. Kennedy, Muna Al-Saffar
      Pages 725-740
  7. Back Matter
    Pages 741-772

About this book

Introduction

Arab populations have their “own” genetic disorders, both universal and particular. Genetic diversity within these source populations, along with the fact that the rates of inbreeding are often high and family sizes are often large, constitute conditions that facilitate the emergence and detection of phenotypes explained notably by autosomal recessive inheritance; in which case, the use of homozygosity gene mapping can facilitate the discovery of the corresponding genes. The present book includes 5 parts dealing with various aspects that relate to the genetic structure of Arabs and minorities within the Arab world as well as genetic disorders prevalent in this part of the world. It includes updated reviews of the genetic disorders in various Arab countries and geographic regions. The focus is primarily, but not exclusively, on the group of single-gene disorders with particular emphasis on autosomal recessive conditions. It further includes epidemiological and clinical data as well as inheritance patterns, mutation and polymorphism data, and available haplotype analysis data. The ethnic and genetic diversity of the Arab populations is discussed as well as aspects of genetic counseling practice in this region together with a proposal for an ethical framework for genetic research and prevention of genetic disorders. The target audience of this book includes human and medical geneticists, genetic counselors, researchers, medical specialists dealing with Arab patients or practicing in Arab countries, medical and genetic counseling students, and nurses.

Keywords

counseling demography diseases epidemiological gene genes genetics health inflammation marriage mutation patients population research syndromes

Editors and affiliations

  • Ahmad S. Teebi
    • 1
  1. 1.Qatar FoundationWeill Cornell Medical College in QatarDohaQatar

Bibliographic information