Sepsis Management


  • Jordi Rello
  • J. Lipman
  • Thiago Lisboa

Table of contents

  1. Front Matter
    Pages i-vi
  2. Jean-Louis Vincent, Marjorie Beumier, Antoine Herpain, Katia Donadello
    Pages 1-6
  3. Rui Moreno, Andrew Rhodes
    Pages 7-22
  4. Andrew Rhodes, Maurizio Cecconi, Rui Moreno
    Pages 23-31
  5. Thiago Lisboa, Jordi Rello
    Pages 33-39
  6. Jorge I. F. Salluh, Fernando Augusto Bozza, André Miguel Japiassu, Márcio Soares
    Pages 41-58
  7. Jan J. De Waele, Inneke De laet
    Pages 59-71
  8. Gordon Y. S. Choi, Gavin M. Joynt, Charles D. Gomersall
    Pages 73-90
  9. Olfa Hamzaoui, Jean-Louis Teboul
    Pages 91-102
  10. Rob Boots
    Pages 103-128
  11. Lee P. Skrupky, Scott T. Micek, Marin H. Kollef
    Pages 129-147
  12. Matteo Bassetti, Malgorzata Mikulska
    Pages 149-170
  13. Duane Funk, Shravan Kethireddy, Anand Kumar
    Pages 219-235
  14. Back Matter
    Pages 237-243

About this book


This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.


Antibiotic use MODS Organ dysfunction Sepsis Severe infections in the ICU

Editors and affiliations

  • Jordi Rello
    • 1
  • J. Lipman
    • 2
  • Thiago Lisboa
    • 3
  1. 1.Unidad de Cuidados CríticosHospital Universitari Joan XXIIITarragonaSpain
  2. 2.Intensive Care FacilityRoyal Brisbane HospitalHerston, BrisbaneAustralia
  3. 3.Unidad de Cuidados CríticosHospital Universitari Joan XXIIITarragonaSpain

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2012
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-642-03518-0
  • Online ISBN 978-3-642-03519-7
  • Buy this book on publisher's site