Small Molecules in Oncology

  • Uwe M. Martens

Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 184)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Protein kinase inhibitors

    1. Front Matter
      Pages 1-1
    2. Cornelius F. Waller
      Pages 3-20
    3. M. Steins, M. Thomas, M. Geißler
      Pages 21-31
    4. Ronan Joseph Kelly, Olivier Rixe
      Pages 33-44
    5. Tanja Schneider-Merck, Martin Trepel
      Pages 45-59
    6. Jens Hasskarl
      Pages 61-70
    7. Daniel Y. C. Heng, Christian Kollmannsberger
      Pages 71-82
    8. Markus Lindauer, Andreas Hochhaus
      Pages 83-102
    9. Alfonso Quintás-Cardama, Theo Daniel Kim, Vince Cataldo, Philipp le Coutre
      Pages 103-117
    10. Gunhild Keller, Philippe Schafhausen, Tim H. Brümmendorf
      Pages 119-127
  3. Epigenetic modifiers

    1. Front Matter
      Pages 130-130
    2. Michael Daskalakis, Nadja Blagitko-Dorfs, Björn Hackanson
      Pages 131-157
    3. Antonia Müller, Mareike Florek
      Pages 159-170
  4. Cell cycle inhibitors

    1. Front Matter
      Pages 172-172
    2. Hermann Einsele
      Pages 173-187
    3. Christian Stock, Massimo Zaccagnini, Michael Schulze, Dogu Teber, Jens J. Rassweiler
      Pages 189-197
    4. R. Wäsch, J. Hasskarl, D. Schnerch, M. Lübbert
      Pages 215-218
  5. Other novel agents

    1. Front Matter
      Pages 220-220

About this book

Introduction

Extensive research into the molecular mechanisms of cancer disease has heralded a new age of targeted therapy. In malignant cells, key proteins that are crucial to tumor growth and survival are now being targeted directly with rationally designed inhibitors. Apart from monoclonal antibodies, small molecule therapeutics such as oncogenic protein kinase inhibitors are attracting a vast amount of investigational attention. This textbook, written by acknowledged experts, provides a broad overview of the small molecules currently used for the treatment of malignant diseases and discusses interesting novel compounds that are in the process of clinical development to combat cancer.

Keywords

Molecular mechanisms of cancer Oncogenic protein kinase inhibitors Targeted therapy Treatment of malignant diseases tumor growth

Editors and affiliations

  • Uwe M. Martens
    • 1
  1. 1.Medizinische Klinik IIISLK-Kliniken Heilbronn GmbHHeilbronnGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-01222-8
  • Copyright Information Springer-Verlag Berlin Heidelberg 2010
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-642-01221-1
  • Online ISBN 978-3-642-01222-8
  • Series Print ISSN 0080-0015
  • About this book