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  • © 2010

Lead-Seeking Approaches

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Part of the book series: Topics in Medicinal Chemistry (TMC, volume 5)

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  • ISBN: 978-3-642-01075-0
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Table of contents (6 chapters)

  1. Front Matter

    Pages i-xiii
  2. High Throughput Screening in the Twenty-First Century

    • Jeff W. Paslay, John E. Morin, Richard K. Harrison
    Pages 25-83
  3. Lead Discovery Using Virtual Screening

    • Jack Andrew Bikker, Lakshmi S. Narasimhan
    Pages 85-124
  4. NMR Spectroscopy in Fragment Based Drug Design

    • Maurizio Pellecchia
    Pages 125-139
  5. Lead Identification

    • John W. Ellingboe, Adam M. Gilbert
    Pages 175-212
  6. Back Matter

    Pages 213-217

About this book

Christopher A. Lipinski: Overview of Hit to Lead: The Medicinal Chemist’s Role from HTS Retest to Lead Optimization Hand Off

Jeff W. Paslay • John E. Morin • Richard K. Harrison: High Throughput Screening in the Twenty - First Century

Jack Andrew Bikker • Lakshmi S.Narasimhan: Lead Discovery Using Virtual Screening

Maurizio Pellecchia: NMR Spectroscopy in Fragment Based Drug Design

Kevin D. Freeman-Cook • Daniel W. Kung: Hit Triage – Medicinal Chemistry Strategies to Improve the Odds of Success in Discovery

John W. Ellingboe • Adam M. Gilbert: Lead Identification

Keywords

  • chemistry
  • medicinal chemistry
  • nuclear magnetic resonance (NMR)
  • spectroscopy

Editors and Affiliations

  • Dept. Neuroscience Chemistry, Pfizer Global Research & Development, Groton CT, USA

    Matthew M. Hayward

Bibliographic Information

  • Book Title: Lead-Seeking Approaches

  • Editors: Matthew M. Hayward, J. A. Bikker, J. W. Ellingboe, K. D. Freeman-Cook, A. M. Gilbert, R. K. Harrison, D. W. Kung, C. A. Lipinski, J. E. Morin, L. S. Narasimhan, J. W. Paslay, M. Pellecchia

  • Series Title: Topics in Medicinal Chemistry

  • DOI: https://doi.org/10.1007/978-3-642-01075-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2010

  • Hardcover ISBN: 978-3-642-01074-3

  • Softcover ISBN: 978-3-642-26106-0

  • eBook ISBN: 978-3-642-01075-0

  • Series ISSN: 1862-2461

  • Series E-ISSN: 1862-247X

  • Edition Number: 1

  • Number of Pages: XIII, 217

  • Number of Illustrations: 26 b/w illustrations, 10 illustrations in colour

  • Topics: Medicinal Chemistry, Neuroscience, Organic Chemistry

Buying options

eBook
USD 189.00
Price excludes VAT (USA)
  • ISBN: 978-3-642-01075-0
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD 249.99
Price excludes VAT (USA)
Hardcover Book
USD 249.99
Price excludes VAT (USA)