Visualizing Immunity

  • Michael Dustin
  • Dorian McGavern

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 334)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Nicholas R.J. Gascoigne, Jeanette Ampudia, Jean-Pierre Clamme, Guo Fu, Carina Lotz, Michel Mallaun et al.
    Pages 31-46
  3. John H. Kehrl, Il-Young Hwang, Chung Park
    Pages 107-127
  4. Alexander Zarbock, Klaus Ley
    Pages 129-152
  5. James J. Moon, Stephen J. McSorley
    Pages 179-198
  6. Vjollca Konjufca, Mark J. Miller
    Pages 199-226
  7. Silvia S. Kang, Dorian B. McGavern
    Pages 227-263
  8. Alexandre Boissonnas, Alix Scholer-Dahire, Luc Fetler, Sebastian Amigorena
    Pages 265-287
  9. Back Matter
    Pages 289-292

About this book

Introduction

The immune system is not bound by a single tissue but is instead bestowed with the challenge of warding off invading pathogens throughout the body. Constant surveillance of the body requires that the immune system be highly mobile and able to purge pathogens from all tissues. Because each tissue presents its own unique architecture and milieu, it is necessary for the immune system to be as malleable as it is dynamic. For example, how the immune system handles a pathogen in the lung can differ significantly from a pathogen encountered in the gut.

Understanding immune complexity in diverse tissue environments is a challenge for researchers. However, advances in imaging have greatly improved our ability to probe the immune system. From snap-shots in time to 4D movies, imaging systems have been used to generate stunning visualizations of immune cells in action throughout the body. These visualizations are not only aesthetically pleasing but they have yielded great advances in our understanding of immune function. This volume provides a synopsis of major insights in immunology revealed using imaging approaches. "Seeing is truly believing", and this volume was assembled to recognize past accomplishments and to provide visions of what the future holds in store in this exciting field.

Keywords

B cell activation Listeria monocytogenes infection T cell T cell activation anti-tumor T cells basal intranodal T cell motility cells central nervous system chemoattract receptor signaling immunity in the CNS infection leukocyte leukocyte recruitment migration tissue

Editors and affiliations

  • Michael Dustin
  • Dorian McGavern

There are no affiliations available

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-540-93864-4
  • Copyright Information Springer Berlin Heidelberg 2009
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-540-93862-0
  • Online ISBN 978-3-540-93864-4
  • Series Print ISSN 0070-217X
  • About this book