Overview
Part of the book series: Ernst Schering Foundation Symposium Proceedings (SCHERING FOUND, volume 2007/4)
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Table of contents (12 papers)
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Front Matter
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Back Matter
Keywords
About this book
In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effects on metabolism with the help of modern analytic technologies to rapidly analyze broad varieties of metabolites in various tissues and bodyfluids (metabonomics).
Bibliographic Information
Book Title: Oncogenes Meet Metabolism
Book Subtitle: From Deregulated Genes to a Broader Understanding of Tumour Physiology
Editors: G. Kroemer, D. Mumberg, H. Keun, B. Riefke, T. Steger-Hartmann, K. Petersen
Series Title: Ernst Schering Foundation Symposium Proceedings
DOI: https://doi.org/10.1007/978-3-540-79478-3
Publisher: Springer Berlin, Heidelberg
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2008
Hardcover ISBN: 978-3-540-79477-6Published: 20 August 2008
Softcover ISBN: 978-3-642-09840-6Published: 30 November 2010
eBook ISBN: 978-3-540-79478-3Published: 25 July 2008
Series ISSN: 0947-6075
Edition Number: 1
Number of Pages: XV, 265
Topics: Oncology, Human Physiology, Analytical Chemistry