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  • © 2008

Molecular Imaging II

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 185/2)

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xxvii
  2. Amplification Strategies

    1. Optical Methods

      • Christoph Bremer
      Pages 3-12
    2. PET and SPECT

      • Uwe Haberkorn
      Pages 13-35
    3. Environment-sensitive and Enzyme-sensitive MR Contrast Agents

      • Manuel Querol, Alexei Bogdanov Jr.
      Pages 37-57
  3. Molecular Targets and Biomarkers for Imaging

    1. Peptides, Multimers and Polymers

      • I. Dijkraaf, H. J. Wester
      Pages 61-92
    2. Small Molecule Receptors as Imaging Targets

      • Aviv Hagooly, Raffaella Rossin, Michael J. Welch
      Pages 93-129
    3. Enzymes/Transporters

      • Regine Garcia Boy, Eva-Maria Knapp, Michael Eisenhut, Uwe Haberkorn, Walter Mier
      Pages 131-143
    4. Phage Peptide Display

      • Jessica Newton, Susan L. Deutscher
      Pages 145-163
  4. Applications: Experimental Imaging

    1. Molecular Imaging: Reporter Gene Imaging

      • Inna Serganova, Phillipp Mayer-Kukuck, Ruimin Huang, Ronald Blasberg
      Pages 167-223
    2. The Use of Ultrasound in Transfection and Transgene Expression

      • Claire Rome, Roel Deckers, Chrit T. W. Moonen
      Pages 225-243
    3. Magnetic Resonance of Mouse Models of Cardiac Disease

      • Karl-Heinz Hiller, Christiane Waller, Axel Haase, Peter M. Jakob
      Pages 245-257
    4. Translational Imaging

      1. Translational Imaging: Imaging of Apoptosis
        • H. William Strauss, Francis Blankenberg, Jean-Luc Vanderheyden, Jonathan Tait
        Pages 259-275
      2. Molecular Imaging of PET Reporter Gene Expression
        • Jung-Joon Min, Sanjiv S. Gambhir
        Pages 277-303
      3. Noninvasive Cell Tracking
        • Fabian Kiessling
        Pages 305-321
      4. Molecular Imaging-guided Gene Therapy of Gliomas
        • Maria A. Rueger, Alexandra Winkeler, Anne V. Thomas, Lutz W. Kracht, Andreas H. Jacobs
        Pages 341-359
  5. Back Matter

    Pages 361-365

About this book

The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is beeing addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.

Reviews

From the reviews:

“Topics covered are intended for a sophisticated multidisciplinary audience. … serves as an introduction to the expansive field of molecular imaging while developing in the reader an understanding of many of the complexities that allow novel approaches to studying the physiology, biochemistry, and molecular biology of intact living systems. … imaging scientists and clinicians who wish to learn more about the most advanced methods and applications of their craft should benefit from the coverage of the topics laid out in this book.” (Geoffrey D. Clarke, Radiology, Vol. 256 (1), July, 2010)

Editors and Affiliations

  • Forschungsschwerpunkt Innovative Krebsdiagnostik und -therapie (E), Deutsches Krebsforschungszentrum, Heidelberg, Germany

    Wolfhard Semmler

  • Nuklearmedizinische Klinik und Poliklinik, Klinikum rechts des Isar des Technischen Universität München, München, Germany

    Markus Schwaiger

Bibliographic Information

Buy it now

Buying options

eBook USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access