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Molecular Imaging

Radiopharmaceuticals for PET and SPECT

  • Shankar Vallabhajosula

About this book

Introduction

Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.

Keywords

Neurology diagnostics molecular imaging nuclear medicine positron emission tomography positron emission tomography (PET) psychiatry radiopharmaceuticals single photon emission computed tomography (SPECT)

Authors and affiliations

  • Shankar Vallabhajosula
    • 1
  1. 1.Citigroup Biomedical Imaging Center (CBIC)Weill Cornell Medical College of Cornell UniversityNew YorkUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-540-76735-0
  • Copyright Information Springer Berlin Heidelberg 2009
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-540-76734-3
  • Online ISBN 978-3-540-76735-0
  • Buy this book on publisher's site