Stress-Activated Protein Kinases

  • Editors
  • Francesc Posas
  • Angel R. Nebreda

Part of the Topics in Current Genetics book series (TCG, volume 20)

Table of contents

  1. Front Matter
    Pages I-XVIII
  2. Lisa Stalheim, Gary L. Johnson
    Pages 1-15
  3. Francisco Iñesta-Vaquera, Guadalupe Sabio, Yvonne Kuma, Ana Cuenda
    Pages 17-32
  4. Eusebio Perdiguero, Pura Muñoz-Cánoves
    Pages 51-79
  5. Ignacio Dolado, Angel R. Nebreda
    Pages 99-128
  6. Sandra Lopez-Aviles, Rosa M. Aligue
    Pages 129-140
  7. Miguel A. Rodríguez-Gabriel, Paul Russell
    Pages 159-170
  8. Fabian Rudolf, Serge Pelet, Matthias Peter
    Pages 187-204
  9. Gerasimos P. Sykiotis, Dirk Bohmann
    Pages 225-241
  10. Alexey Kotlyarov, Matthias Gaestel
    Pages 243-260
  11. Mercedes Rincón, Roger J. Davis
    Pages 261-281
  12. Nicholas T. Crump, Ya Ting Han, Louis C. Mahadevan
    Pages 283-297
  13. Malin Hult, Per Sunnerhagen
    Pages 299-310
  14. Back Matter
    Pages 311-312

About this book


To maximize the probability of survival, cells need to coordinate their intracellular activities in response to changes in the extracellular environment. MAP kinase cascades play an important role in the transduction of signals inside eukaryotic cells. In particular, stress stimuli result in the rapid activation of a highly conserved group of MAP kinases, known as SAPKs (Stress-Activated Protein Kinases). These kinases coordinate the generation of adaptive responses that are essential for cell survival, which include the modulation of several aspects of cell physiology from metabolism to gene expression.

In this book, leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signalling in various systems from yeast to mammals. These include various chapters on regulatory mechanisms as well as the contribution of the SAPK signalling pathways to processes such as gene expression, metabolism, cell cycle regulation, immune responses and tumorigenesis.


Activation Cell Cycle Regulation Kinase Phosphorylation Signalling Stress Adaptation Stress Response gene expression metabolism regulation saccharomyces cerevisiae transcription translation

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2008
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-540-75568-5
  • Online ISBN 978-3-540-75569-2
  • Series Print ISSN 1610-2096
  • Buy this book on publisher's site