About this book
This book covers different aspects of the rare neoplasms – malignant mesothelioma and pseudomyxoma peritonei. The monograph includes up-to-date information on etiology, pathogenesis and diagnostics of malignant mesothelioma and pseudomyxoma peritonei, as well as detailed description of surgical and combined treatment of patients with these diseases. The book comprises a large illustrative material presented by schemes and original micrographs that represent pathological and immunohistochemical specific features of these malignancies, demonstrate the stages of surgical operations and hyperthermic intraperitoneal chemotherapy, and show the results of experimental studies.The book includes validated discussion on etiology and pathogenesis of malignant mesothelioma and pseudomyxoma peritonei, differential diagnosis and treatment of these diseases. The scope is really extensive and involves, for instance, a description of the technique of cytoreductive surgeries and regimens of intraperitoneal hyperthermic chemoperfusion, whereas a particular section discusses experimental ground for optimal regimens of hyperthermia, local chemotherapy and adoptive immunotherapy by cytokine induced killers. The final section presents the most recent data about perspective approaches for immunotherapy of malignant mesothelioma and pseudomyxoma peritonei with cell based technologies and target drugs including inhibitors of immune checkpoints. The co-authors of the book are leading specialists in this area, surgeons and scientists who present the results of their research along with the analysis of the state-of-the-art of this problem.
The book is designed for a wide audience of students and professors of medical universities and schools, specialists of research and diagnostic centers, practical oncologists and immunologists, as well as doctors of different medical areas.