Progress in the Chemistry of Organic Natural Products 107

  • A. Douglas Kinghorn
  • Heinz Falk
  • Simon Gibbons
  • Jun'ichi Kobayashi
  • Yoshinori Asakawa
  • Ji-Kai Liu

Part of the Progress in the Chemistry of Organic Natural Products book series (POGRCHEM, volume 107)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Joshua M. Henkin, Yulin Ren, Djaja Djendoel Soejarto, A. Douglas Kinghorn
    Pages 1-94

About this book


The first review describes examples of very promising compounds discovered from plants acquired from Africa, Southeast Asia, the Americas, and the Caribbean region with potential anticancer activity. These include plant secondary metabolites of the diphyllin lignan, penta[b]benzofuran, triterpenoid, and tropane alkaloid types.

The second review presents 40 more erythrinan alkaloids, which were either new or were missed out in the last major reviews, bringing to a total of 154 known erythrinan alkaloids known to date. The reported pharmacological activities of the new and known alkaloids showed a greater bias towards central nervous system and related activities. Other prominent activities reported were antifeedant or insecticidal, cytotoxicity/anti­tumor/anti­cancer/estrogenic, antiprotozoal, antiinflammatory, antioxidant, antifungal and antiviral activities.


tropical plants anticancer agents Erythrinan alkaloids pharmacological activities CNS activity

Editors and affiliations

  1. 1.College of PharmacyThe Ohio State UniversityColumbusUSA
  2. 2.Institute of Organic ChemistryJohannes Kepler UniversityLinzAustria
  3. 3.UCL School of PharmacyUniversity College London, ResearchLondonUK
  4. 4.Grad. School of Pharmaceutical ScienceHokkaido UniversityFukuokaJapan
  5. 5.Faculty of Pharmaceutical SciencesTokushima Bunri UniversityTokushimaJapan
  6. 6.School of Pharmaceutical SciencesSouth-Central Univ. for NationalitiesWuhanChina

Bibliographic information