This book provides an introduction to the Eastern Mediterranean region and introduces the concept of the Eastern Mediterranean as a new regional subsystem. Due to recent events in contemporary international politics, the Eastern Mediterranean can be seen as a laboratory where the balance of power among Great Powers and regional states are being tested. Written by leading academics in their respective fields, this book addresses key developments in the area and argues that the Eastern Mediterranean should be viewed as a distinct region. Particular emphasis is given to the initiatives undertaken by Israel, Greece, Cyprus, and Turkey; the role played by the United States and Russia; and the issues of energy, migration, and Islamic terrorism. Bringing together relevant information and theoretical debates, this book will be of interest to graduate students and academics studying international relations and politics in the Eastern Mediterranean, as well as policymakers and journalists who want to have a clearer understanding of developments in the region.