Overview
Written by leaders in genetic and developmental research on scoliosis and developmental studies of the spine
The only book currently on the market that incorporates knowledge in clinical, genetic, and developmental aspects of scoliosis
Recent developments in key clinical and moltecular genetic studies of these disorders are also discussed
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Table of contents (8 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field.
This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.
Editors and Affiliations
About the editors
Kenro Kusumi, Ph.D., is a Professor in the School of Life Sciences at Arizona State University.Dr. Kusumi’s current research focuses on genomic analysis of spinal development and regeneration, and their applications to developing novel therapies for scoliosis and other spinal disorders.
Sally L. Dunwoodie, Ph.D., is a Professor at the University of New South Wales and Laboratory Head in the Developmental Biology and Stem Cell Division at the Victor Chang Cardiac Research Institute in Sydney. Dr. Dunwoodie's research focuses on identifying genetic and environmental factors that disrupt embryogenesis and cause birth defects.
Bibliographic Information
Book Title: The Genetics and Development of Scoliosis
Editors: Kenro Kusumi, Sally L. Dunwoodie
DOI: https://doi.org/10.1007/978-3-319-90149-7
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG, part of Springer Nature 2018
Hardcover ISBN: 978-3-319-90148-0Published: 22 June 2018
Softcover ISBN: 978-3-030-07944-4Published: 15 January 2019
eBook ISBN: 978-3-319-90149-7Published: 12 June 2018
Edition Number: 2
Number of Pages: XII, 199
Number of Illustrations: 17 b/w illustrations, 12 illustrations in colour
Topics: Human Genetics, Developmental Biology, Human Physiology, Orthopedics