© 2019

Endoscopic and Keyhole Cranial Base Surgery

  • James J. Evans
  • Tyler J. Kenning
  • Christopher Farrell
  • Varun R. Kshettry

Table of contents

  1. Front Matter
    Pages i-xx
  2. Endoscopic Endonasal Surgery

    1. Front Matter
      Pages 1-1
    2. Tyler J. Kenning, Varun R. Kshettry, Christopher J. Farrell, James J. Evans
      Pages 3-8
    3. Maria Peris-Celda, Carlos D. Pinheiro-Neto, Rowan Valentine, Albert L. Rhoton
      Pages 9-33
    4. Cristine Klatt-Cromwell, Brian Thorp, Charles S. Ebert Jr, Deanna Sasaki-Adams, Matthew G. Ewend, Adam M. Zanation
      Pages 35-45
    5. Ankush Chandra, Manish K. Aghi
      Pages 47-60
    6. Sacit Bulent Omay, Vijay K. Anand, Theodore H. Schwartz
      Pages 61-69
    7. Luigi Maria Cavallo, Domenico Solari, Alberto Di Somma, Waleed A. Azab, Paolo Cappabianca
      Pages 71-80
    8. Georgios A. Zenonos, Stefan Lieber, Juan C. Fernandez-Miranda
      Pages 81-99
    9. Moujahed Labidi, Shunya Hanakita, Kentaro Watanabe, Anne-Laure Bernat, Nouman Aldahak, Schahrazad Bouazza et al.
      Pages 101-117
  3. Keyhole Cranial Surgery

    1. Front Matter
      Pages 119-119
    2. Varun R. Kshettry, Tyler J. Kenning, James J. Evans, Christopher J. Farrell
      Pages 121-128
    3. Gordon Mao, Nouman Aldahak, Khaled Abdel Aziz
      Pages 129-139
    4. Behnam Rezai Jahromi, Felix Göhre, Juhana Frösen, Danil A. Kozyrev, Juha A. Hernesniemi
      Pages 141-147
    5. Melvin Field, Luke H. Pearson
      Pages 149-161
    6. Hasan A. Zaidi, Peter Nakaji
      Pages 163-172
    7. Anil Kumar Roy, Nefize Turan, Gustavo Pradilla
      Pages 173-183
    8. Rafael Uribe-Cardenas, Mark M. Souweidane
      Pages 185-193
  4. Target-Based Comparison of Approaches

    1. Front Matter
      Pages 195-195
    2. Michael W. McDermott, Henry W. S. Schroeder, Verena Gellner
      Pages 197-222

About this book


The first two sections of this text address endoscopic and keyhole surgical procedures for cranial base and deep brain structures.  These sections provide a comprehensive, state-of-the art review of this minimally invasive field and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in cranial base surgery.  The philosophy, techniques, indications and limitations of endoscopic and keyhole cranial base surgery are covered in detail. This reference includes a discussion of the basic principles of these approaches as well as the preoperative planning, intraoperative pearls, and reconstruction techniques.  The thorough descriptions of the practical and technical aspects are accompanied by extensive illustrations, figures and operative images.  

Extending beyond the technical details of these procedures, this text provides a third section that focuses on a thorough analysis and comparison of the endoscopic, keyhole and traditional open approaches to specific intracranial regions.  Utilizing a “target-based” approach, the utility of each surgical technique is evaluated in regard to accessing pathology of the anterior, middle and posterior fossa cranial base as well as the deep central regions of the brain. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.

 Endoscopic and Keyhole Cranial Base Surgery will be a valuable resource to specialists in optimizing surgical results and improving patient outcomes.


Supraorbital Keyhole Approaches Mini-Pterional Craniotomy Transorbital Keyhole Approaches Intracranial Surgery Sinonasal and Parasellar Anatomy Cavernous Sinus Posterior Cranial Fossa Olfactory Groove Meningiomas Intracranial Hemorrhage

Editors and affiliations

  • James J. Evans
    • 1
  • Tyler J. Kenning
    • 2
  • Christopher Farrell
    • 3
  • Varun R. Kshettry
    • 4
  1. 1.Cranial Base and Pituitary Surgery Department of NeurosurgeryThomas Jefferson UniversityPhiladelphiaUSA
  2. 2.Pituitary and Cranial Base Surgery, Department of NeurosurgeryAlbany Medical CenterAlbanyUSA
  3. 3.Cranial Base and Pituitary Surgery Department of NeurosurgeryThomas Jefferson UniversityPhiladelphiaUSA
  4. 4.Skull Base, Pituitary and Cerebrovascular Surgery Department of NeurosurgeryCleveland ClinicClevelandUSA

About the editors

James J. Evans, MD

Professor of Neurological Surgery and Otolaryngology 

Director of Cranial Base and Pituitary Surgery

Thomas Jefferson University

909 Walnut Street

2nd Floor, COB Bldg.

Philadelphia, PA 19107

Tyler J. Kenning, MD

Assistant Professor of Neurosurgery

Director, Pituitary and Minimally Invasive Cranial Base Surgery Program

Director, Brain Tumor and Neuro-oncology Clinic

Albany Medical Center

47 New Scotland Ave, MC-10

Albany, NY 12208

Christopher Farrell, MD

Assistant Professor of Neurosurgery

Thomas Jefferson University

909 Walnut Street

2nd Floor, COB Bldg.

Philadelphia, PA 19107

Varun R. Kshettry, MD

Associate Staff, Skull Base and Cerebrovascular Surgery

Minimally Invasive Cranial Base and Pituitary Surgery Program

Department of Neurological Surgery

Cleveland Clinic

Cleveland, OH


Bibliographic information

  • Book Title Endoscopic and Keyhole Cranial Base Surgery
  • Editors James J. Evans
    Tyler J. Kenning
    Christopher Farrell
    Varun R. Kshettry
  • DOI
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-319-64378-6
  • eBook ISBN 978-3-319-64379-3
  • Edition Number 1
  • Number of Pages XX, 396
  • Number of Illustrations 31 b/w illustrations, 207 illustrations in colour
  • Topics Neurosurgery
  • Buy this book on publisher's site


“The approach is highly instructive, and a whole separate volume full of difficult cases with this sort of teaching approach would be welcomed by legions of skull base surgery learners around the globe.” (Kumar Vasudevan, Neurosurgery, Vol. 86 (1), 2020)

“The audience for this book is residents with an interest in skull base surgery as well as fellows and neurosurgeons/ENT surgeons involved in the treatment of deep seated and skull base lesions.” (Cristian Gragnaniello, Doody's Book Reviews, December 20, 2019)