Precision Molecular Pathology of Prostate Cancer

  • Brian D. Robinson
  • Juan Miguel Mosquera
  • Jae Y. Ro
  • Mukul Divatia
Book

Part of the Molecular Pathology Library book series (MPLB)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. General Principles

    1. Front Matter
      Pages 1-1
    2. Beerinder S. Karir, Bishoy M. Faltas, Scott T. Tagawa
      Pages 3-12
    3. Padraic O’Malley
      Pages 13-26
    4. Shaham Beg, Francesca Khani, Brian D. Robinson
      Pages 37-56
    5. John P. Greene, Stephen P. Finn
      Pages 57-78
    6. Francesca Khani, Brian D. Robinson
      Pages 79-98
    7. Yanjing Li, Jiaoti Huang
      Pages 99-113
  3. Molecular Signatures of Primary Prostate Cancer

    1. Front Matter
      Pages 115-115
    2. Olivier Elemento
      Pages 129-135
    3. Andrea Sboner
      Pages 137-151
    4. Michael Ittmann
      Pages 153-167
    5. Anne Offermann, Sven Perner
      Pages 169-192
    6. Fátima Valdés-Mora, Clare Stirzaker
      Pages 193-211
    7. Samantha E. T. Larkin, Benjamin Abbott, Michael D. Brown, Thomas R. Jackson, Noel W. Clarke, Paul A. Townsend
      Pages 213-236
    8. Stefano Cacciatore, Giorgia Zadra, Massimo Loda
      Pages 237-258
    9. Zhenyu Jia, Chung Lee, Xiaolin Zi, Michael McClelland, Dan Mercola
      Pages 259-275
  4. Molecular Signatures of Advanced Prostate Cancer

    1. Front Matter
      Pages 277-277

About this book

Introduction

This volume focuses on our current understanding of the molecular underpinnings of prostate cancer and their potential application for precision medicine approaches.  The emergence and applications of new technologies has allowed for a rapid expansion of our understanding of the molecular basis of prostate cancer and has revealed a remarkable genetic heterogeneity that may underlie the clinically variable behavior of the disease.  The book consists of five sections which provide insight about the following: 

(1) General principles; 
(2) Molecular signatures of primary prostate cancer; 
(3) Molecular signatures of advanced prostate cancer; 
(4) Key molecular pathways in prostate cancer development and progression; 
(5) Precision medicine approach: Diagnosis, treatment, prognosis.  

Precision Molecular Pathology of Prostate Cancer is an important resource for the practicing oncologist, urologist, and pathologist, and will also be useful for researchers in the prostate cancer community.  

Keywords

Castration resistant Cytoskeletal function Epithelial-mesenchymal transition Neuroendocrine Prostatic adenocarcinoma Tyrosine kinase signaling

Editors and affiliations

  • Brian D. Robinson
    • 1
  • Juan Miguel Mosquera
    • 2
  • Jae Y. Ro
    • 3
  • Mukul Divatia
    • 4
  1. 1.Pathology and Laboratory MedicineNew York-Presbyterian Hospital, Weill Cornell Medical CollegeNew YorkUSA
  2. 2.Pathology and Laboratory MedicineNew York-Presbyterian Hospital, Weill Cornell Medical CollegeNew YorkUSA
  3. 3.Institute for Academic MedicineHouston Methodist Hospital Pathology and Genomic Medicine, Weill Medical College of Cornell UniversityHoustonUSA
  4. 4.Institute for Academic MedicineHouston Methodist Hospital Pathology and Genomic Medicine, Weill Medical College of Cornell UniversityHoustonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-64096-9
  • Copyright Information Springer International Publishing AG 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-64094-5
  • Online ISBN 978-3-319-64096-9
  • Series Print ISSN 1935-987X
  • Series Online ISSN 1935-9888
  • About this book