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  • © 2018

Behavioral Pharmacology of Neuropeptides: Oxytocin

  • Gives insight into a new era of social psychopharmacology based on endogenous neuromodulators

  • Discusses early-life treatment of social-cognitive deficiencies

  • Provides cutting-edge information on "precision medicine"

Part of the book series: Current Topics in Behavioral Neurosciences (CTBN, volume 35)

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eBook USD 189.00
Price excludes VAT (USA)
  • ISBN: 978-3-319-63739-6
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 249.99
Price excludes VAT (USA)
Hardcover Book USD 249.99
Price excludes VAT (USA)

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Table of contents (26 chapters)

  1. Front Matter

    Pages i-ix
  2. Animal Research Section

    1. Front Matter

      Pages 1-1
    2. Oxytocin Modulation of Neural Circuits

      • Mariela Mitre, Jessica Minder, Egzona X. Morina, Moses V. Chao, Robert C. Froemke
      Pages 31-53
    3. Oxytocin and Olfaction

      • Lars-Lennart Oettl, Wolfgang Kelsch
      Pages 55-75
    4. Oxytocin and Steroid Actions

      • Gustav F. Jirikowski, Scott D. Ochs, Jack D. Caldwell
      Pages 77-95
    5. Oxytocin and Social Relationships: From Attachment to Bond Disruption

      • Oliver J. Bosch, Larry J. Young
      Pages 97-117
    6. Oxytocin and Parental Behaviors

      • Chihiro Yoshihara, Michael Numan, Kumi O. Kuroda
      Pages 119-153
    7. The Role of Oxytocin in Social Buffering: What Do Primate Studies Add?

      • Catherine Crockford, Tobias Deschner, Roman M. Wittig
      Pages 155-173
    8. Oxytocin and Aggression

      • Trynke R. de Jong, Inga D. Neumann
      Pages 175-192
    9. Oxytocin Signaling in Pain: Cellular, Circuit, System, and Behavioral Levels

      • Pierrick Poisbeau, Valery Grinevich, Alexandre Charlet
      Pages 193-211
    10. Oxytocin and Animal Models for Autism Spectrum Disorder

      • Shlomo Wagner, Hala Harony-Nicolas
      Pages 213-237
    11. Oxytocin Signaling in the Early Life of Mammals: Link to Neurodevelopmental Disorders Associated with ASD

      • Françoise Muscatelli, Michel G. Desarménien, Valery Matarazzo, Valery Grinevich
      Pages 239-268
  3. Human Research Section

    1. Front Matter

      Pages 289-289
    2. Oxytocin and Human Evolution

      • C. Sue Carter
      Pages 291-319
    3. Overview of Human Oxytocin Research

      • Keith M. Kendrick, Adam J. Guastella, Benjamin Becker
      Pages 321-348
    4. Oxytocin and Facial Emotion Recognition

      • Mark A. Ellenbogen
      Pages 349-374
    5. Oxytocin and Social Cognition

      • Andreas Ebert, Martin Brüne
      Pages 375-388
    6. Oxytocin and Interpersonal Relationships

      • Alexandra Patin, Dirk Scheele, Rene Hurlemann
      Pages 389-420

About this book

This volume collects cutting-edge expert reviews in the oxytocin field and will be of interest to a broad scientific audience ranging from social neuroscience to clinical psychiatry. The role of the neuropeptide oxytocin in social behaviors is one of the earliest and most significant discoveries in social neuroscience. Influential studies in animal models have delineated many of the neural circuits and genetic components that underlie these behaviors. These discoveries have inspired researchers to investigate the effects of oxytocin on brain and behavior in humans and its potential relevance as a treatment for psychiatric disorders including borderline personality disorder and autism and schizophrenia spectrum disorders. In fact, there is no established social psychopharmacology in Psychiatry, and oxytocin can be seen as the first endogenous agent specifically addressing social-cognitive impairment in psychiatric disorders, with animal research suggesting that it could be especially efficient in the early postnatal period. From a human perspective, it is crucial to understand more precisely who can benefit from potential oxytocin-related treatments, which outcome measures will best represent their effects, how they should be administered, and what brain mechanisms are likely involved in mediating their effects. This type of “precision medicine” approach is in line with the research domain criteria defined by the U.S. National Institute of Mental Health.

Keywords

  • Oxytocin
  • clinical research
  • preclincal research
  • health and disease
  • intranasal administration

Editors and Affiliations

  • Department of Psychiatry, University of Bonn, Bonn, Germany

    Rene Hurlemann

  • Schaller Research Group on Neuropeptides German Cancer Research Center, University of Heidelberg, Heidelberg, Germany

    Valery Grinevich

  • Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany

    Valery Grinevich

Bibliographic Information

Buying options

eBook USD 189.00
Price excludes VAT (USA)
  • ISBN: 978-3-319-63739-6
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 249.99
Price excludes VAT (USA)
Hardcover Book USD 249.99
Price excludes VAT (USA)