Overview
- Reviews the current knowledge to critically evaluate the causal link between cell division machinery and disease
- Identifies key open questions in the field and means for exploring them
- Explores cell division and links to common disorders including cancer, aging and infertility
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1002)
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About this book
This book critically evaluates the causal link between cell division machinery and disease. Further, it identifies key open questions in the field and the means for exploring them. Throughout the various chapters, internationally known contributors present the evidence for and against a causal link between key elements of the cell division machinery and diseases such as cancer, neuropathologies, aging, and infertility. A more clinically oriented chapter further discusses the current and future applications of anti-mitotic drugs in these diseases. Cell Division Machinery and Disease is essential reading for graduate or advanced graduate students, researchers or scientists working on cell division as well as clinicians interested in the molecular mechanisms of the discussed diseases.
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Keywords
Table of contents (9 chapters)
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Front Matter
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Back Matter
Editors and Affiliations
About the editors
Monica Gotta is Ordinary Professor at the Medical Faculty of the University of Geneva. She has previously worked as a Swiss-National Science Foundation Professor at the ETH Zurich. Her research interests are the (a)symmetric cell divisions of C. elegans embryos and human cells. She has published 43 papers and 1 book chapter. She has also been awarded an EMBO YIP award.
Patrick Meraldi is Associate Professor at the Medical Faculty of the University of Geneva. He has previously worked as a Swiss-National Science Foundation Professor at the ETH Zurich. His research interest is primarily in the field of chromosome segregation in human cells. He has published 49 papers and 2 book chapters. He has also been awarded an EURYI award , an EMBO YIP award and the Walther Flemming Medal.
Patrick Meraldi is Associate Professor at the Medical Faculty of the University of Geneva. He has previously worked as a Swiss-National Science Foundation Professor at the ETH Zurich. His research interest is primarily in the field of chromosome segregation in human cells. He has published 49 papers and 2 book chapters. He has also been awarded an EURYI award , an EMBO YIP award and the Walther Flemming Medal.
Bibliographic Information
Book Title: Cell Division Machinery and Disease
Editors: Monica Gotta, Patrick Meraldi
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-319-57127-0
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017
Hardcover ISBN: 978-3-319-57125-6Published: 21 June 2017
Softcover ISBN: 978-3-319-86083-1Published: 02 August 2018
eBook ISBN: 978-3-319-57127-0Published: 09 June 2017
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XIV, 235
Number of Illustrations: 1 b/w illustrations, 32 illustrations in colour
Topics: Cell Cycle Analysis, Cell Physiology, Cancer Research