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  • © 2017

Modern Meta-Analysis

Review and Update of Methodologies

  • A series of novel methodologies unpublished so far have been covered

  • The book has been jointly written by a clinician and a mathematical statistician

  • This is the first book implementing machine learning into the field of meta-analysis

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xvi
  2. Meta-analysis in a Nutshell

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 1-22
  3. Mathematical Framework

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 23-41
  4. Meta-analysis and the Scientific Method

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 43-50
  5. Meta-analysis and Random Effect Analysis

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 51-62
  6. Meta-analysis with Statistical Software

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 63-77
  7. Meta-analyses of Randomized Controlled Trials

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 79-91
  8. Meta-analysis of Observational Plus Randomized Studies

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 93-100
  9. Meta-analysis of Observational Studies

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 101-114
  10. Meta-regression

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 115-126
  11. Meta-analysis of Diagnostic Studies

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 127-134
  12. Meta-Meta-analysis

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 135-143
  13. Network Meta-analysis

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 145-155
  14. Random Intercepts Meta-analysis

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 157-165
  15. Probit Meta-regression

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 167-175
  16. Meta-analysis with General Loglinear Models

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 177-183
  17. Meta-analysis with Variance Components

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 185-193
  18. Ensembled Correlation Coefficients

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 195-204
  19. Ensembled Accuracies

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 205-216
  20. Multivariate Meta-analysis

    • Ton J. Cleophas, Aeilko H. Zwinderman
    Pages 217-231

About this book

Modern meta-analyses do more than combine the effect sizes of a series of similar studies. Meta-analyses are currently increasingly applied for any analysis beyond the primary analysis of studies, and for the analysis of big data. This 26-chapter book was written for nonmathematical professionals of medical and health care, in the first place, but, in addition, for anyone involved in any field involving scientific research. The authors have published over twenty innovative meta-analyses from the turn of the century till now. This edition will review the current state of the art, and will use for that purpose the methodological aspects of the authors' own publications, in addition to other relevant methodological issues from the literature.

Are there alternative works in the field? Yes, there are, particularly in the field of psychology. Psychologists have invented meta-analyses in 1970, and have continuously updated methodologies. Although very interesting, their work, just like the whole discipline of psychology, is rather explorative in nature, and so is their focus to meta-analysis. Then, there is the field of epidemiologists. Many of them are from the school of angry young men, who publish shocking news all the time, and JAMA and other publishers are happy to publish it. The reality is, of course, that things are usually not as bad as they seem. Finally, some textbooks, written by professional statisticians, tend to use software programs with miserable menu programs and requiring lots of syntax to be learnt. This is prohibitive to clinical and other health professionals.

 

The current edition is the first textbook in the field of meta-analysis entirely written by two clinical scientists, and it consists of many data examples and step by step analyses, mostly from the authors' own clinical research. 

Authors and Affiliations

  • Department of Medicine, Albert Schweitzer Hospital, Sliedrecht, The Netherlands

    Ton J. Cleophas

  • Department of Epidemiology and Biostatistics, Academic Medical Center, Amsterdam, The Netherlands

    Aeilko H. Zwinderman

About the authors

The authors are well-qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015), and Professor Cleophas is past-president of the American College of Angiology (2000-2002). From their expertise they should be able to make adequate selections of modern methods for clinical data analysis for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 17 years, and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics.

The authors as professors and teachers in statistics at universities in The Netherlands and France for the most part of their lives, are convinced that the scientific method of statistical reasoning and hypothesis testing is little used by physicians and other health workers, and they hope that the current production will help them find the appropriate ways for answering their scientific questions.

Three textbooks complementary to the current production and written by the same authors are Statistics applied to clinical studies 5th edition, 2012, Machine learning in medicine a complete overview, 2015, SPSS for starters and 2nd levelers, 2015, all of them edited by Springer Heidelberg Germany.


Bibliographic Information

  • Book Title: Modern Meta-Analysis

  • Book Subtitle: Review and Update of Methodologies

  • Authors: Ton J. Cleophas, Aeilko H. Zwinderman

  • DOI: https://doi.org/10.1007/978-3-319-55895-0

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2017

  • Hardcover ISBN: 978-3-319-55894-3Published: 10 May 2017

  • Softcover ISBN: 978-3-319-85775-6Published: 25 July 2018

  • eBook ISBN: 978-3-319-55895-0Published: 02 May 2017

  • Edition Number: 1

  • Number of Pages: XVI, 314

  • Number of Illustrations: 183 b/w illustrations, 63 illustrations in colour

  • Topics: Medicine/Public Health, general

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access