Glial Amino Acid Transporters

  • Arturo Ortega
  • Arne Schousboe

Part of the Advances in Neurobiology book series (NEUROBIOL, volume 16)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Eunsook Lee, Pratap Karki, James Johnson Jr, Peter Hong, Michael Aschner
    Pages 1-12
  3. Beatriz López-Corcuera, Cristina Benito-Muñoz, Carmen Aragón
    Pages 13-32
  4. Herminia Pasantes-Morales
    Pages 33-53
  5. Francisco Zafra, Ignacio Ibáñez, David Bartolomé-Martín, Dolores Piniella, Marina Arribas-Blázquez, Cecilio Giménez
    Pages 55-83
  6. Sepehr Eskandari, Samantha L. Willford, Cynthia M. Anderson
    Pages 85-116
  7. Lauren Taylor Rosenblum, Davide Trotti
    Pages 117-136
  8. Maria E. K. Lie, Anas Al-Khawaja, Maria Damgaard, Anne S. Haugaard, Arne Schousboe, Andrew N. Clarkson et al.
    Pages 137-167
  9. Edna Suárez-Pozos, Donají Chi-Castañeda, Arturo Ortega
    Pages 185-198
  10. Donají Chi-Castañeda, Edna Suárez-Pozos, Arturo Ortega
    Pages 199-224
  11. Roberto Elizondo-Vega, María Angeles García-Robles
    Pages 255-267
  12. Germán Fernando Gutiérrez Aguilar, Ivan Alquisiras-Burgos, Mónica Espinoza-Rojo, Penélope Aguilera
    Pages 269-282
  13. Arne Schousboe, Petrine Wellendorph, Bente Frølund, Rasmus P. Clausen, Povl Krogsgaard-Larsen
    Pages 283-296
  14. Hans Christian Cederberg Helms, Carsten Uhd Nielsen, Helle Sønderby Waagepetersen, Birger Brodin
    Pages 297-314
  15. Maria Damgaard, Anne Stæhr Haugaard, Stefanie Kickinger, Anas Al-Khawaja, Maria E. K. Lie, Gerhard F. Ecker et al.
    Pages 315-332
  16. Back Matter
    Pages 333-341

About this book


Our current knowledge of the role of macroglia in the physiology of the nervous system has been shaped on by both the established role of oligodendrocytes and Schwann cells in the propagation of the action potential and by the concept of the tripartite synapse.

In both cases, integral membrane proteins such as receptors and transporters are crucial for the proper function of these cells. This book is an extensive review of the contribution of glial membrane transporters.  Model transporters are analysed in terms of their structure, distribution and involvement in major functions and/or pathologies of the nervous system. It is important to note that a particular emphasis has been placed in the rather unexplored signalling properties of glial transporters. Likewise, strategies toward the design of novel compounds that target membrane transporters are discussed.

Different points of view of the involvement and contribution of glial transporters are presented in this volume, and the contrast of these interpretations invites the readers to broaden their interest of membrane transporters beyond the chapters of this book. No intention was made to provide a certain order to the chapters of the book; in fact any of them can be read independently.

We want to express our appreciation to the contributors for their enthusiasm in the preparation of their excellent chapters that will certainly provide a fresh perspective of the exponential accumulation of knowledge that has been published in the last few years and unequivocally changing the concept of glial physiology.

It is our hope that this book provides a major input to the fascinating field of membrane transporters as fundamental proteins for the establishment of a better understanding of glia-neuron interactions.



Amino Acid Transporters GABA Gene Expression Regulation Glia Cells Signaling

Editors and affiliations

  • Arturo Ortega
    • 1
  • Arne Schousboe
    • 2
  1. 1.Department of ToxicologyCinvestav-IPN México CityMéxicoMexico
  2. 2.Department of Drug Design and Pharmacology, Faculty of Health and Medical SciencesUniversity of CopenhagenCopenhagenDenmark

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-55767-0
  • Online ISBN 978-3-319-55769-4
  • Series Print ISSN 2190-5215
  • Series Online ISSN 2190-5223
  • Buy this book on publisher's site