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Microdomains in the Cardiovascular System

  • Viacheslav Nikolaev
  • Manuela Zaccolo

Part of the Cardiac and Vascular Biology book series (Abbreviated title: Card. vasc. biol.)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Cyclic Nucleotide Microdomains

    1. Front Matter
      Pages 1-1
    2. Nadja I. Bork, Viacheslav O. Nikolaev
      Pages 3-15
    3. Shailesh R. Agarwal, Rennolds S. Ostrom, Robert D. Harvey
      Pages 17-35
    4. John M. Redden, Kimberly L. Dodge-Kafka, Michael S. Kapiloff
      Pages 37-57
    5. Alessandra Ghigo, Flora Pirozzi, Mingchuan Li, Emilio Hirsch
      Pages 85-95
    6. Ibrahim Bedioune, Pierre Bobin, Jérôme Leroy, Rodolphe Fischmeister, Grégoire Vandecasteele
      Pages 97-116
    7. Lauren Wills, Bracy A. Fertig, George S. Baillie
      Pages 161-173
    8. Lise Román Moltzau, Silja Meier, Kjetil Wessel Andressen, Finn Olav Levy
      Pages 245-271
    9. Brian Leei Lin, David A. Kass, Dong I. Lee
      Pages 273-290
  3. Calcium Microdomains

    1. Front Matter
      Pages 291-291
    2. Alexey V. Glukhov, Anamika Bhargava, Julia Gorelik
      Pages 293-319
    3. Karin P. Hammer, Lars S. Maier
      Pages 321-340
    4. A. M. Gómez, T. R. R. Mesquita, J. J. Mercadier, J. L. Álvarez, J. P. Benitah
      Pages 361-386

About this book

Introduction

The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second messengers such as cAMP, cGMP, calcium and their role in microdomain signaling are discussed. The book offers and explains methodical approaches and technical ways how to successfully analyze microdomain signaling, also in the context of disease. It further provides scientific perspectives and strategies that are based on the concept of signaling within microdomains and that can revolutionize pharmacology and eventually lead to the effective treatment of cardiovascular diseases in future.
This book is written for scientists in cardiovascular research, pharmacology, molecular and cellular biology as well as medical doctors in cardiology, angiology and nephrology. 

Keywords

microdomain signaling cardiovascular cardiomyocyte second messenger

Editors and affiliations

  • Viacheslav Nikolaev
    • 1
  • Manuela Zaccolo
    • 2
  1. 1.Institute of Experimental Cardiovascular ResearchUniversity Medical CenterHamburg-EppendorfGermany
  2. 2.Department of Physiology, Anatomy and GeneticsUniversity of OxfordOxfordUnited Kingdom

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-54579-0
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-54578-3
  • Online ISBN 978-3-319-54579-0
  • Series Print ISSN 2509-7830
  • Series Online ISSN 2509-7849
  • Buy this book on publisher's site