Shiga toxins

A Review of Structure, Mechanism, and Detection

  • Christopher J. Silva
  • David L. Brandon
  • Craig B. Skinner
  • Xiaohua He

Part of the Food Microbiology and Food Safety book series (FMFS)

Also part of the Research and Development book sub series (RESDEV)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Christopher J. Silva, David L. Brandon, Craig B. Skinner, Xiaohua He
    Pages 1-4
  3. Christopher J. Silva, David L. Brandon, Craig B. Skinner, Xiaohua He
    Pages 5-19
  4. Christopher J. Silva, David L. Brandon, Craig B. Skinner, Xiaohua He
    Pages 21-45
  5. Christopher J. Silva, David L. Brandon, Craig B. Skinner, Xiaohua He
    Pages 47-61
  6. Christopher J. Silva, David L. Brandon, Craig B. Skinner, Xiaohua He
    Pages 63-75
  7. Christopher J. Silva, David L. Brandon, Craig B. Skinner, Xiaohua He
    Pages 77-100
  8. Christopher J. Silva, David L. Brandon, Craig B. Skinner, Xiaohua He
    Pages 101-113
  9. Back Matter
    Pages 115-118

About this book

Introduction

This book presents an overview of Shiga toxin-producing E. coli (STEC), with in-depth coverage of key areas such as recent Shiga toxin-related poisonings in Europe and the US, the structure, production, and mechanism of action of Shiga toxin, and current methods of detection.

The globalization of food production has introduced new risk factors and intensified existing hazards, complicating the assurance of food safety. Foodborne illness outbreaks, such as those related to STEC, are becoming more common and more dangerous. The threat that these bacterial toxins pose to the food supply is magnified by the frequent occurrence and severity of Shiga toxin-caused disease.   As a result, STEC and their toxins remain a primary concern in food safety.

This review serves as a key resource for scientists in the field and public health and regulatory officials charged with maintaining food safety. This book also looks to the future of treatment of Shiga toxin-associated disease, specifically the translation of lab bench science into clinical therapeutic strategies.

Keywords

verotoxin E. coli bacterial toxins foodborne illness food biosecurity

Authors and affiliations

  • Christopher J. Silva
    • 1
  • David L. Brandon
    • 2
  • Craig B. Skinner
    • 3
  • Xiaohua He
    • 4
  1. 1.United States Department of Agriculture, Agricultural Research ServiceWestern Regional Research CenterAlbanyUSA
  2. 2.United States Department of Agriculture, Agricultural Research ServiceWestern Regional Research CenterAlbanyUSA
  3. 3.United States Department of Agriculture, Agricultural Research ServiceWestern Regional Research CenterAlbanyUSA
  4. 4.United States Department of Agriculture, Agricultural Research ServiceWestern Regional Research CenterAlbanyUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-50580-0
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-50579-4
  • Online ISBN 978-3-319-50580-0
  • About this book