Skip to main content
SpringerLink
Log in
Book cover

The Actin Cytoskeleton and Bacterial Infection

  • Book
  • © 2017

Overview

Editors:
  1. Hans Georg Mannherz

    1. Institut für Anatomie, Abteilung für Anatomie und Molekulare Embryologie, Ruhr-Universität Bochum, Bochum, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Presents a comprehensive overview of the actin modifying actions of bacterial toxins
  • Bridges the gap between common knowledge, new findings and new concepts for therapeutic approaches
  • A valuable resource for microbiologists, cell biologists, and clinicians whose work involves infectious diseases
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 399)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 179.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (11 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Actin: Structure, Function, Dynamics, and Interactions with Bacterial Toxins

    • Sonja Kühn, Hans Georg Mannherz
    Pages 1-34

  3. Formation of Nanotube-Like Protrusions, Regulation of Septin Organization and Re-guidance of Vesicle Traffic by Depolymerization of the Actin Cytoskeleton Induced by Binary Bacterial Protein Toxins

    • Carsten Schwan, Klaus Aktories
    Pages 35-51

  4. Photorhabdus luminescens Toxins TccC3 and TccC5 Affect the Interaction of Actin with Actin-Binding Proteins Essential for Treadmilling

    • Alexander E. Lang, Sonja Kühn, Hans Georg Mannherz
    Pages 53-67

  5. Comparative Studies of Actin- and Rho-Specific ADP-Ribosylating Toxins: Insight from Structural Biology

    • Hideaki Tsuge, Toshiharu Tsurumura, Akiyuki Toda, Haruka Murata, Waraphan Toniti, Toru Yoshida
    Pages 69-86

  6. Pathogenic Mechanisms of Actin Cross-Linking Toxins: Peeling Away the Layers

    • Elena Kudryashova, David B. Heisler, Dmitri S. Kudryashov
    Pages 87-112

  7. ActA of Listeria monocytogenes and Its Manifold Activities as an Important Listerial Virulence Factor

    • Helena Pillich, Madhu Puri, Trinad Chakraborty
    Pages 113-132

  8. Actin-Dependent Regulation of Borrelia burgdorferi Phagocytosis by Macrophages

    • Xenia Naj, Stefan Linder
    Pages 133-154

  9. New Aspects on Bacterial Effectors Targeting Rho GTPases

    • Emmanuel Lemichez
    Pages 155-174

  10. Type III Secreted Virulence Factors Manipulating Signaling to Actin Dynamics

    • Theresia E. B. Stradal, Sonia C. P. Costa
    Pages 175-199

  11. Acting on Actin: Rac and Rho Played by Yersinia

    • Martin Aepfelbacher, Manuel Wolters
    Pages 201-220

  12. Bacterial Actins and Their Interactors

    • Pananghat Gayathri
    Pages 221-242
Back to top

Keywords

About this book

This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the properties of the intracellular actin cytoskeleton for their own purposes. Bacterial factors either modify actin directly as the main component of this part of the cytoskeleton or functionally subvert regulatory or signalling proteins terminating at the actin cytoskeleton.
In short, this volume provides an overview of the various tricks bacteria have evolved to “act on actin” in order to hijack this essential host cell component for their own needs. As such, it will be of interest to scientists from many fields, as well as clinicians whose work involves infectious diseases.

Editors and Affiliations

  • Institut für Anatomie, Abteilung für Anatomie und Molekulare Embryologie, Ruhr-Universität Bochum, Bochum, Germany

    Hans Georg Mannherz

About the editor

Hans Georg MannherzRuhr-Universität Bochum
Institut für Anatomie
Abteilung für Anatomie und molekulare Embryologie
e-mail: Hans.Mannherz@ruhr-uni-bochum.de



Bibliographic Information

  • Book Title: The Actin Cytoskeleton and Bacterial Infection

  • Editors: Hans Georg Mannherz

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-319-50047-8

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017

  • Hardcover ISBN: 978-3-319-50046-1Published: 13 February 2017

  • Softcover ISBN: 978-3-319-84305-6Published: 13 July 2018

  • eBook ISBN: 978-3-319-50047-8Published: 07 February 2017

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: X, 242

  • Topics: Medical Microbiology, Pharmacology/Toxicology

Publish with us

Policies and ethics

Back to top

Search

Navigation