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Metabolomics: From Fundamentals to Clinical Applications

  • Alessandra Sussulini

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 965)

Also part of the Proteomics, Metabolomics, Interactomics and Systems Biology book sub series (PMISB, volume 965)

Table of contents

  1. Front Matter
    Pages i-x
  2. Fundamentals and Analytical Methodologies in Metabolomics

    1. Front Matter
      Pages 1-1
    2. Aline Klassen, Andréa Tedesco Faccio, Gisele André Baptista Canuto, Pedro Luis Rocha da Cruz, Henrique Caracho Ribeiro, Marina Franco Maggi Tavares et al.
      Pages 3-17
    3. Andrew J. Chetwynd, Warwick B. Dunn, Giovanny Rodriguez-Blanco
      Pages 19-44
    4. Clement Heude, Jay Nath, John Bosco Carrigan, Christian Ludwig
      Pages 45-76
    5. Aline Soriano Lopes, Elisa Castañeda Santa Cruz, Alessandra Sussulini, Aline Klassen
      Pages 77-98
    6. Karina Trevisan Rodrigues, Zuzana Cieslarová, Marina Franco Maggi Tavares, Ana Valéria Colnaghi Simionato
      Pages 99-141
  3. Statistical Analysis and Data Interpretation

  4. Applications and Future Trends of Metabolomics in Clinical Cases

    1. Front Matter
      Pages 207-207
    2. Emily Grace Armitage, Michal Ciborowski
      Pages 209-234
    3. Annalaura Mastrangelo, Coral Barbas
      Pages 235-263
    4. Sumit Sethi, Mirian A. F. Hayashi, Banny S. Barbosa, João G. M. Pontes, Ljubica Tasic, Elisa Brietzke
      Pages 265-290
    5. Samy Emara, Sara Amer, Ahmed Ali, Yasmine Abouleila, April Oga, Tsutomu Masujima
      Pages 323-343
  5. Back Matter
    Pages 345-350

About this book

Introduction

This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics are also presented.

For researches already experienced in metabolomics, the book will be useful as an updated definitive reference. For beginners in the field and graduate students, the book will provide detailed information about concepts and experimental aspects in metabolomics, as well as examples and perspectives of applications of this strategy to clinical questions.

Keywords

metabolomics metabolite profiling mass spectrometry nuclear magnetic resonance data analysis statistics chemometrics lipidomics clinical metabolomics

Editors and affiliations

  • Alessandra Sussulini
    • 1
  1. 1.University of Campinas (UNICAMP) Institute of Chemistry Laboratory of Bioanalytics and Integrated Omics (LaBIOmics)CampinasBrazil

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-47656-8
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-47655-1
  • Online ISBN 978-3-319-47656-8
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • Buy this book on publisher's site