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Organogenetic Gene Networks

Genetic Control of Organ Formation

  • A unique account of the development of gene networks written by some of the world’s leading experts in the field

  • A unique description of disease development as a result of faulty genetic and signalling pathways

  • A comprehensive account of gene networks in a number of model systems

  • Includes supplementary material: sn.pub/extras

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-vi
  2. Models for Studying Organogenetic Gene Networks in the 21st Century

    • James Castelli-Gair Hombría, Paola Bovolenta
    Pages 1-7
  3. Organogenesis of the C. elegans Vulva and Control of Cell Fusion

    • Nathan Weinstein, Benjamin Podbilewicz
    Pages 9-56
  4. Organogenesis of the Drosophila Respiratory System

    • Rajprasad Loganathan, Yim Ling Cheng, Deborah J. Andrew
    Pages 151-211
  5. Organogenesis of the Zebrafish Kidney

    • Hao-Han Chang, Richard W. Naylor, Alan J. Davidson
    Pages 213-233
  6. Morphogenetic Mechanisms of Inner Ear Development

    • Berta Alsina, Andrea Streit
    Pages 235-258
  7. Vertebrate Eye Gene Regulatory Networks

    • Juan R. Martinez-Morales
    Pages 259-274
  8. Vertebrate Eye Evolution

    • Juan R. Martinez-Morales, Annamaria Locascio
    Pages 275-298
  9. Principles of Early Vertebrate Forebrain Formation

    • Florencia Cavodeassi, Tania Moreno-Mármol, María Hernandez-Bejarano, Paola Bovolenta
    Pages 299-317
  10. Control of Organogenesis by Hox Genes

    • J. Castelli-Gair Hombría, C. Sánchez-Higueras, E. Sánchez-Herrero
    Pages 319-373
  11. Back Matter

    Pages 375-376

About this book

All animals, including humans, derive from a single cell, which possesses all the genetic instructions needed to define how the animal will look like. However, during development, the millions of cells that derive from the zygote will only select part of this genetic information to give rise to the various organs of the body. The coordination of different cell behaviours during development results in the formation of specialized tissues and organs giving rise to highly adapted animals.  This book provides an overview of how this diversification is achieved during organ formation and how it may have evolved.  Conserved cellular processes are presented using examples from selected vertebrate and invertebrate species that illustrate how developmental biologists are solving the complex puzzle of organ formation. This volume is aimed to students, researchers and medical doctors alike who want to find a simple but rigorous introduction on how gene networks control organ formation.<

Editors and Affiliations

  • CSIC/JA/UPO, Andalusian Centre for Developmental Biology (CABD), CSIC/JA/UPO, Seville, Spain

    James Castelli-Gair Hombría

  • CSIC-UAM, Center for Molecular Biology Severo Ochoa and CIBERER, CSIC-UAM, Madrid, Spain

    Paola Bovolenta

About the editors

James Castelli-Gair HombríaAndalusian Centre for Developmental Biology (CABD)



Paola Bovolenta

Center for Molecular Biology Severo Ochoa, CSIC-UAM and CIBERER, Madrid, Spain





Bibliographic Information

  • Book Title: Organogenetic Gene Networks

  • Book Subtitle: Genetic Control of Organ Formation

  • Editors: James Castelli-Gair Hombría, Paola Bovolenta

  • DOI: https://doi.org/10.1007/978-3-319-42767-6

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-42765-2Published: 07 September 2016

  • Softcover ISBN: 978-3-319-82659-2Published: 14 June 2018

  • eBook ISBN: 978-3-319-42767-6Published: 26 August 2016

  • Edition Number: 1

  • Number of Pages: VI, 376

  • Number of Illustrations: 56 illustrations in colour

  • Topics: Gene Function, Embryology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access