Protein Therapeutics

  • Zuben E. Sauna
  • Chava Kimchi-Sarfaty
Book

Part of the Topics in Medicinal Chemistry book series (TMC, volume 21)

Table of contents

  1. Front Matter
    Pages i-xiii
    PDF
  2. Protein Production in Eukaryotic Cells
    Kripa Ram, Diane Hatton, Sanjeev Ahuja, Jean Bender, Alan Hunter, Richard Turner
    Pages 1-39
  3. Production of Protein Therapeutics in the Quality by Design (QbD) Paradigm
    Anurag S. Rathore, Sumit K. Singh
    Pages 41-67
  4. Characterization of Therapeutic Proteins
    E. B. Struble, N. Kirschbaum, J. Liu, E. Marszal, M. Shapiro
    Pages 69-121
  5. Immunogenicity Lessons Learned from the Clinical Development of Vatreptacog Alfa, A Recombinant Activated Factor VII Analog, in Hemophilia with Inhibitors
    Kasper Lamberth, Karin Nana Weldingh, Silke Ehrenforth, Mette Ribel Chéhadé, Henrik Østergaard
    Pages 123-160
  6. The Art of Gene Redesign and Recombinant Protein Production: Approaches and Perspectives
    Anton A. Komar
    Pages 161-177
  7. Back Matter
    Pages 179-182
    PDF

About this book

Introduction


Keywords

Bio-betters Bioengineering Biosimilars Factor IX-FC Fusion Protein Factor VIIa Analogs Monoclonal Antibodies Personalized Medicine Protein Therapeutics Quality-by-design Replacement Protein-therapeutics

Editors and affiliations

  • Zuben E. Sauna
    • 1
  • Chava Kimchi-Sarfaty
    • 2
  1. 1.Division of Plasma Protein Therapeutics, Office of Tissues and Advanced Therapies, FDA | CBER | OTATFederal Research Center at White OakSilver SpringUSA
  2. 2.Division of Plasma Protein Therapeutics, Office of Tissues and Advanced Therapies, FDA | CBER | OTATFederal Research Center at White OakSilver SpringUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-41818-6
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-3-319-41816-2
  • Online ISBN 978-3-319-41818-6
  • Series Print ISSN 1862-2461
  • Series Online ISSN 1862-247X
  • About this book