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Heat Shock Protein Inhibitors

Success Stories

  • Shelli R. McAlpine
  • Adrienne Lesley Edkins

Part of the Topics in Medicinal Chemistry book series (TMC, volume 19)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Jeanette McConnell, Yao Wang, Shelli McAlpine
    Pages 1-20
  3. Laura K. Buckton, Yao Wang, Jeanette R. McConnell, Shelli R. McAlpine
    Pages 55-80
  4. Sharan R. Srinivasan, Hao Shao, Xiaokai Li, Jason E. Gestwicki
    Pages 131-162
  5. Eva-Rachele Pesce, Gregory L. Blatch, Adrienne L. Edkins
    Pages 163-195
  6. George Sharbeen, Shelli McAlpine, Phoebe Phillips
    Pages 197-219
  7. Rashid Mehmood, Shelli R. McAlpine
    Pages 221-234
  8. Back Matter
    Pages 235-238

About this book

Introduction

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.


 

Keywords

Chemical Probes Dual Hsp70 Modulators Dual Hsp90 Modulators Heat Shock Proteins Hsp 40 Hsp47 Hsp70 Inhibitors Hsp70/hsp40 Interactions Hsp90 Molecular Chaperones

Editors and affiliations

  • Shelli R. McAlpine
    • 1
  • Adrienne Lesley Edkins
    • 2
  1. 1.School of ChemistryUniversity of New South WalesSidneyAustralia
  2. 2.Biomedical Biotechnology Research Unit (BioBRU); Department of Biochemistry and MicrobiologyRhodes UniversityGrahamstownSouth Africa

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-32607-8
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-3-319-32605-4
  • Online ISBN 978-3-319-32607-8
  • Series Print ISSN 1862-2461
  • Series Online ISSN 1862-247X
  • Buy this book on publisher's site