Cerebral Autoregulation

1. Front Matter

   Pages i-xv

   PDF

2. Physiological Basis

   • Stephen Payne

   Pages 1-18

3. Measurement Techniques

   • Stephen Payne

   Pages 19-38

4. Mathematical Models

   • Stephen Payne

   Pages 39-56

5. Analysis Techniques

   • Stephen Payne

   Pages 57-74

6. Clinical Conditions

   • Stephen Payne

   Pages 75-119

7. Conclusions

   • Stephen Payne

   Pages 121-125

This Brief provides a comprehensive introduction to the control of blood flow in the brain. Beginning with the basic physiology of autoregulation, the author goes on to discuss measurement techniques, mathematical models, methods of analysis, and relevant clinical conditions, all within this single volume. The author draws together this disparate field, and lays the groundwork for future research directions.

The text gives an up-to-date review of the state of the art in cerebral autoregulation, which is particularly relevant as cerebral autoregulation moves from the laboratory to the bedside. Cerebral Autoregulation will be useful to researchers in the physical sciences such as mathematical biology, medical physics, and biomedical engineering whose work is concerned with the brain. Researchers in the medical sciences and clinicians dealing with the brain and blood flow, as well as industry professionals developing techniques such as ultrasound, MRI, and CT will also find this Brief of interest.

• Modelling blood flow
• Haemodynamics
• Cerebral vasculature
• Control of blood flow
• Cerebral circulation

• Department of Engineering Science, University of Oxford, Oxford, United Kingdom

  Stephen Payne

Stephen Payne is currently an Associate Professor at the University of Oxford (since 2006) and has been working in the field of cerebral blood flow and autoregulation for over 10 years, with a number of grants in this area and a substantial number (>60) of research papers published. He has also supervised over 20 PhD students, most of whom have worked in this and related areas.