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Scleroderma

From Pathogenesis to Comprehensive Management

  • Book
  • © 2017

Overview

Editors:
  1. John Varga

    1. Feinberg School of Medicine, Northwestern University, Chicago, USA

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  2. Christopher P. Denton

    1. Division of Medicine, Department of Inflammation, Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, Royal Free Hospital, London, United Kingdom

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  3. Fredrick M. Wigley

    1. Division of Rheumatology, Johns Hopkins University, Baltimore, USA

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  4. Yannick Allanore

    1. Service de Rhumatologie A, INSERMU1016, Universit. Paris Descartes, Hôpital Cochin, Paris, France

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  5. Masataka Kuwana

    1. Department of Allergy and Rheumatology, Nippon Medical School, Graduate School of Medicine, Tokyo, Japan

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  • Provides a concise synthesis of current concepts of pathogenesis and modern approaches to management of systemic sclerosis
  • New edition includes new chapters on personalized medicine, cancer complications, and global perspectives on scleroderma
  • Presents an integrated multidisciplinary approach to comprehensive patient care
  • Chapter authors are international leaders specializing in the field

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Table of contents (57 chapters)

  1. Front Matter

    Pages i-xxxv
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  2. Introduction

    1. Front Matter

      Pages 1-1
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    2. Historical Perspective of Scleroderma

      • Christopher P. Denton, Marco Matucci-Cerinic
      Pages 3-7

  3. Epidemiology, Genetics and Classification

    1. Front Matter

      Pages 9-9
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    2. Epidemiology, Environmental, and Infectious Risk Factors

      • Jammie K. Barnes, Luc Mouthon, Maureen D. Mayes
      Pages 11-24

    3. Genetic Factors

      • Shervin Assassi, Yannick Allanore
      Pages 25-38

    4. Disease Subsets in Clinical Practice

      • Robyn T. Domsic, Thomas A. Medsger Jr.
      Pages 39-48

    5. Evolving Concepts of Diagnosis and Classification

      • Sindhu R. Johnson, Lorinda Chung, Jaap Fransen, Frank H. J. Van den Hoogen
      Pages 49-64

    6. Overlap Syndromes

      • Pia Moinzadeh, Christopher P. Denton
      Pages 65-74

    7. Juvenile Localized and Systemic Scleroderma

      • Lauren V. Graham, Amy S. Paller, Ivan Foeldvari
      Pages 75-89

    8. Morphea (Localized Scleroderma)

      • Noelle M. Teske, Heidi T. Jacobe
      Pages 91-113

    9. Scleroderma Mimics

      • Laura K. Hummers, Alan Tyndall
      Pages 115-123

    10. Systems Biology Approaches to Understanding the Pathogenesis of Systemic Sclerosis

      • J. Matthew Mahoney, Jaclyn N. Taroni, Michael L. Whitfield
      Pages 125-129

  4. The Biological Basis of Systemic Sclerosis

    1. Front Matter

      Pages 131-131
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    2. Introduction: The Etiopathogenesis of Systemic Sclerosis – An Integrated Overview

      • Carol Feghali-Bostwick, John Varga
      Pages 133-139

    3. Pathology of Systemic Sclerosis

      • Lisa M. Rooper, Frederic B. Askin
      Pages 141-159

    4. Inflammation and Immunity

      • Francesco Boin, Carlo Chizzolini
      Pages 161-195

    5. Autoantibodies as Markers and Possible Mediators of Scleroderma Pathogenesis

      • Kimberly Doering Maurer, Antony Rosen
      Pages 197-205

    6. The Clinical Aspects of Autoantibodies

      • Masataka Kuwana, Thomas A. Medsger Jr.
      Pages 207-220

    7. Mechanisms of Vascular Disease

      • Mirko Manetti, Bashar Kahaleh
      Pages 221-244
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Keywords

About this book

Comprised of the authoritative work of international experts, this fully-updated second edition of Scleroderma builds upon the well-regarded approach in the first edition to provide integrated, concise, and up-to-date synthesis of current concepts of pathogenesis and modern approaches to management of systemic sclerosis (scleroderma). With a multidisciplinary approach to comprehensive care, this book is easily accessible for health care professionals in many fields. The new edition includes extensive updated material based on major developments in the field, with new chapters on personalized medicine, cancer complications, global perspectives on scleroderma, and more. It presents a succinct and thoughtful synthesis of current pathomechanistic concepts, providing a valuable reference tool for basic and translational investigators working in the field. Scleroderma: From Pathogenesis to Comprehensive Management serves as an essential, all-inclusive resource for rheumatologists, pulmonologists, cardiologists, gastroenterologists, nephrologists and all those involved in the care of scleroderma patients.

Editors and Affiliations

  • Feinberg School of Medicine, Northwestern University, Chicago, USA

    John Varga

  • Division of Medicine, Department of Inflammation, Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, Royal Free Hospital, London, United Kingdom

    Christopher P. Denton

  • Division of Rheumatology, Johns Hopkins University, Baltimore, USA

    Fredrick M. Wigley

  • Service de Rhumatologie A, INSERMU1016, Universit. Paris Descartes, Hôpital Cochin, Paris, France

    Yannick Allanore

  • Department of Allergy and Rheumatology, Nippon Medical School, Graduate School of Medicine, Tokyo, Japan

    Masataka Kuwana

About the editors

John Varga, MD

John and Nancy Hughes Distinguished Professor

Feinberg School of Medicine

Director, Northwestern Scleroderma Program

Chicago, Illinois, USA​

 

Christopher P. Denton, PhD, FRCP

Professor of Experimental Rheumatology

Centre for Rheumatology and Connective Tissue Diseases

Division of Medicine

University College London

London, United Kingdom

 

Fredrick M. Wigley, MD

Martha McCrory Professor of Medicine

Department of Medicine/Rheumatology

The Johns Hopkins University School of Medicine

Baltimore, Maryland, USA

 

Yannick Allanore, MD

Service de Rhumatologie A

Université Paris Descartes,

Hôpital Cochin

Paris, France

 

Masataka Kuwana, MD, PhD

Professor

Department of Allergy and Rheumatology

Nippon Medical School GraduateSchool of Medicine

Tokyo, Japan


Bibliographic Information

  • Book Title: Scleroderma

  • Book Subtitle: From Pathogenesis to Comprehensive Management

  • Editors: John Varga, Christopher P. Denton, Fredrick M. Wigley, Yannick Allanore, Masataka Kuwana

  • DOI: https://doi.org/10.1007/978-3-319-31407-5

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media New York 2017

  • Hardcover ISBN: 978-3-319-31405-1Published: 17 November 2016

  • Softcover ISBN: 978-3-319-81033-1Published: 23 June 2018

  • eBook ISBN: 978-3-319-31407-5Published: 07 November 2016

  • Edition Number: 2

  • Number of Pages: XXXV, 743

  • Number of Illustrations: 17 b/w illustrations, 174 illustrations in colour

  • Topics: Rheumatology, Pneumology/Respiratory System, Dermatology

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