Microsystems for Enhanced Control of Cell Behavior

Fundamentals, Design and Manufacturing Strategies, Applications and Challenges

  • Andrés Díaz Lantada

Part of the Studies in Mechanobiology, Tissue Engineering and Biomaterials book series (SMTEB, volume 18)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Fundamentals

    1. Front Matter
      Pages 1-1
    2. Andrés Díaz Lantada
      Pages 3-14
  3. Design and Manufacturing Technologies and Strategies

    1. Front Matter
      Pages 47-47
    2. Andrés Díaz Lantada, Jeffrey Resnick, Javier Mousa, Miguel Ángel de Alba, Stefan Hengsbach, Milagros Ramos Gómez
      Pages 115-145
  4. Applications

    1. Front Matter
      Pages 175-175
    2. Andrés Díaz Lantada, Pilar Lafont Morgado, Pedro Ortego García
      Pages 177-189
    3. Andrés Díaz Lantada, Alberto Bustamante, Alisa Morss Clyne, Rebecca Urbano, Adam C. Canver, Josefa Predestinación García Ruíz et al.
      Pages 191-208
    4. Andrés Díaz Lantada, Adrián de Blas Romero, Josefa Predestinación García Ruíz, Hernán Alarcón Iniesta, Stefan Hengsbach, Volker Piotter
      Pages 209-225
    5. Andrés Díaz Lantada, Enrique Colomer Mayola, María Consuelo Huerta Gómez de Merodio, Alban Muslija, Josefa Predestinación García Ruíz, Hernán Alarcón Iniesta
      Pages 227-247
    6. Andrés Díaz Lantada, Diego Curras, Javier Mousa, Stefan Hengsbach
      Pages 249-268
    7. Andrés Díaz Lantada, Adrián de Blas Romero, Santiago Valido Moreno, Diego Curras, Miguel Téllez, Martin Schwentenwein et al.
      Pages 269-285

About this book


This handbook focuses on the entire development process of biomedical microsystems that promote special interactions with cells. Fundamentals of cell biology and mechanobiology are described as necessary preparatory input for design tasks. Advanced design, simulation, and micro/nanomanufacturing resources, whose combined use enables the development of biomedical microsystems capable of interacting at a cellular level, are covered in depth. A detailed series of chapters is then devoted to applications based on microsystems that offer enhanced cellular control, including microfluidic devices for diagnosis and therapy, cell-based sensors and actuators (smart biodevices), microstructured prostheses for improvement of biocompatibility, microstructured and microtextured cell culture matrices for promotion of cell growth and differentiation, electrophoretic microsystems for study of cell mechanics, microstructured and microtextured biodevices for study of cell adhesion and dynamics, and biomimetic microsystems (including organs-on-chips), among others. Challenges relating to the development of reliable in vitro biomimetic microsystems, the design and manufacture of complex geometries, and biofabrication are also discussed.


Biofabrication Biomedical Microsystems Biomimetic Design Mechanobiology Micromanufacturing Technology Tissue Engineering

Editors and affiliations

  • Andrés Díaz Lantada
    • 1
  1. 1.Mechanical EngineeringUniversidad Politecnica de MadridMadridSpain

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-29328-8
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Engineering
  • Print ISBN 978-3-319-29326-4
  • Online ISBN 978-3-319-29328-8
  • Series Print ISSN 1868-2006
  • Series Online ISSN 1868-2014
  • About this book