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Evolutionary Bioinformatics

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  • © 2016

Overview

  • This title is unique in emphasising non-genic aspects of bioinformatics, and linking modern evolutionary biology to a history that extends back to the nineteenth century
  • Identifies the types of information that genomes transmit and shows how competition between different types is resolved in the genomes of different organisms
  • Illustrates how forms of information that we are familiar with are related to forms we are less familiar with
  • Includes supplementary material: sn.pub/extras

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Table of contents (20 chapters)

  1. Information and DNA

  2. Parity and Non-parity

  3. Variation and Speciation

  4. Conflict Within Genomes

  5. Conflict Between Genomes

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About this book

Now in its third edition and supplemented with more online material, this book aims to make the "new" information-based (rather than gene-based) bioinformatics intelligible both to the "bio" people and the "info" people. Books on bioinformatics have traditionally served gene-hunters, and biologists who wish to construct family trees showing tidy lines of descent. While dealing extensively with the exciting topics of gene discovery and database-searching, such books have hardly considered genomes as information channels through which multiple forms and levels of information have passed through the generations. This “new bioinformatics” contrasts with the "old" gene-based bioinformatics that so preoccupies previous texts. Forms of information that we are familiar with (mental, textual) are related to forms with which we are less familiar (hereditary). The book extends a line of evolutionary thought that leads from the nineteenth century (Darwin, Butler, Romanes, Bateson), through the twentieth (Goldschmidt, White), and into the twenty first (the final works of the late Stephen Jay Gould). Long an area of controversy, diverging views may now be reconciled.

Authors and Affiliations

  • Dept of Biomedical and Molecular Sci, Queen’s University, Kingston, Canada

    Donald R. Forsdyke

About the author

Donald Forsdyke graduated from St. Mary's Hospital, London University, UK in 1961. After house appointments at St.Mary's (Medical Unit and Department of Psychiatry) and the Addenbrooke's Hospital, Cambridge (Surgery), he began research in Molecular Biology and Cellular Immunology at the Department of Biochemistry, Cambridge (Ph.D. 1967). He was appointed to what was then the Department of Biochemistry at Queen's University in 1968. In 2013 he became President of the John Austin Society for the History of Medicine and Science.

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