Skip to main content
  • Textbook
  • © 2016

Clinical Data Analysis on a Pocket Calculator

Understanding the Scientific Methods of Statistical Reasoning and Hypothesis Testing

  • The medical and health care uses the scientific method little, the book addresses how to daily use it
  • Statistical software programs are experienced as black boxes to non mathematiciens
  • All specific advantages of pocket calculators are summarized

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 99.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (60 chapters)

  1. Front Matter

    Pages i-xxiii
  2. Continuous Outcome Data

    1. Front Matter

      Pages 1-1
    2. Data Spread, Standard Deviations

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 3-6
    3. Data Summaries, Histograms, Wide and Narrow Gaussian Curves

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 7-11
    4. Null-Hypothesis Testing with Graphs

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 13-18
    5. Null-Hypothesis Testing with the T-Table

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 19-23
    6. One-Sample Continuous Data (One-Sample T-Test, One-Sample Wilcoxon Test)

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 25-29
    7. Paired Continuous Data (Paired T-Test, Wilcoxon Signed Rank Test)

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 31-36
    8. Unpaired Continuous Data (Unpaired T-Test, Mann-Whitney)

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 37-43
    9. Kendall-Tau Regression for Ordinal Data

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 51-56
    10. Paired Continuous Data, Analysis with Help of Correlation Coefficients

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 57-63
    11. Power Equations

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 65-70
    12. Sample Size Calculations

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 71-74
    13. Confidence Intervals

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 75-78
    14. Equivalence Testing Instead of Null-Hypothesis Testing

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 79-82
    15. Noninferiority Testing Instead of Null-Hypothesis Testing

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 83-86
    16. Superiority Testing Instead of Null-Hypothesis Testing

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 87-91
    17. Missing Data Imputation

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 93-97
    18. Bonferroni Adjustments

      • Ton J. Cleophas, Aeilko H. Zwinderman
      Pages 99-102

About this book

In medical and health care the scientific method is little used, and statistical software programs are experienced as black box programs producing lots of p-values, but little answers to scientific questions. The pocket calculator analyses appears to be, particularly, appreciated, because they enable medical and health professionals and students for the first time to understand the scientific methods of statistical reasoning and hypothesis testing. So much so, that it can start something like a new dimension in their professional world. In addition, a number of statistical methods like power calculations and required sample size calculations can be performed more easily on a pocket calculator, than using a software program. Also, there are some specific advantages of the pocket calculator method. You better understand what you are doing. The pocket calculator works faster, because far less steps have to be taken, averages can be used. The current nonmathematical book is complementary to the nonmathematical "SPSS for Starters and 2nd Levelers" (Springer Heidelberg Germany 2015, from the same authors), and can very well be used as its daily companion.

Authors and Affiliations

  • Department Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands

    Ton J. Cleophas

  • Dept. Epidemiology and Biostatistics, Academic Medical Center, Amsterdam, The Netherlands

    Aeilko H. Zwinderman

About the authors

The authors are well-qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015), and Professor Cleophas is past-president of the American College of Angiology (2000-2002). From their expertise they should be able to make adequate selections of modern methods for clinical data analysis for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 17 years, and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics.

The authors as professors and teachers in statistics at universities in The Netherlands and France for the most part of their lives, are convinced that the scientific method of statistical reasoning and hypothesis testing is little used by physicians and other health workers, and they hope that the current productionwill help them find the appropriate ways for answering their scientific questions.   

Three textbooks complementary to the current production and written by the same authors are Statistics applied to clinical studies 5th edition, 2012, Machine learning in medicine a complete overview, 2015, SPSS for starters and 2nd levelers, 2015, all of them edited by Springer Heidelberg Germany.

Bibliographic Information

  • Book Title: Clinical Data Analysis on a Pocket Calculator

  • Book Subtitle: Understanding the Scientific Methods of Statistical Reasoning and Hypothesis Testing

  • Authors: Ton J. Cleophas, Aeilko H. Zwinderman

  • DOI: https://doi.org/10.1007/978-3-319-27104-0

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-27103-3Published: 29 January 2016

  • Softcover ISBN: 978-3-319-80074-5Published: 30 March 2018

  • eBook ISBN: 978-3-319-27104-0Published: 22 January 2016

  • Edition Number: 2

  • Number of Pages: XXIII, 334

  • Number of Illustrations: 41 b/w illustrations, 24 illustrations in colour

  • Topics: Biomedicine general, Entomology, Pharmacy, Statistics for Life Sciences, Medicine, Health Sciences

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 99.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access