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  • Open Access
  • © 2016

Non-Vitamin K Antagonist Oral Anticoagulants

A Concise Guide

Authors:

(view affiliations)
  • A concise yet comprehensive guide that provides an accessible and up-to-date introductory overview to agents that target the coagulation cascade for thromboprophylaxis

  • Developed with an emphasis on recent evidence-based information

  • Describes both established approaches to anticoagulation as well as emerging therapies

  • Written by high-profile, renowned cardiovascular experts

Table of contents (4 chapters)

  1. Front Matter

    Pages i-vi
  2. Introduction

    • Eduard Shantsila, Gregory YH Lip
    Pages 1-6Open Access
  3. Direct Thrombin Inhibitors

    • Eduard Shantsila, Gregory YH Lip
    Pages 7-24Open Access
  4. Factor Xa Inhibitors

    • Eduard Shantsila, Gregory YH Lip
    Pages 25-71Open Access
  5. Conclusions

    • Eduard Shantsila, Gregory YH Lip
    Pages 73-76Open Access

About this book

This book is an essential guide to the medical treatment of thrombosis and presents core principles of anticoagulant therapeutics as well as drug recommendations. Written by recognized experts in the field, this concise, accessible handbook provides a unique and valuable resource in the cardiovascular field, both for those currently in training, and for those already in clinical or research practice.
 

Keywords

  • Atrial Fibrillation
  • Coagulation
  • Factor Xa
  • Thromboembolism
  • Stroke
  • Acute Coronary Syndromes

Authors and Affiliations

  • University of Birmingham Institute of Cardiovascular Sciences, Birmingham, UK

    Eduard Shantsila, Gregory YH Lip

About the authors

Professor Gregory YH Lip is Professor of Cardiovascular Medicine at
the University of Birmingham, and Visiting Professor of Haemostasis,
Thrombosis, and Vascular Sciences in the School of Life and Health
Sciences at the University of Aston in Birmingham, UK.
Professor Lip is a member of the scientific documents committee of
the European Heart Rhythm Association (EHRA), and serves on the board
of the Working Group on Hypertension of the Heart of the European
Society of Cardiology (ESC). He is also a member of the Working Groups
of Thrombosis and Cardiovascular Pharmacology of the ESC.

Professor Lip has acted as Clinical Adviser for the UK National
Institute for Health and Clinical Excellence (NICE) guidelines on atrial
fibrillation (AF) management. He was on the writing committee for
the 8th American College of Chest Physicians (ACCP) Antithrombotic
Therapy Guidelines for Atrial Fibrillation, as well as various guidelines
and/or position statements from the EHRA, including the EHRA statement
on defining endpoints for AF management, and the EHRA guidelines
for antithrombotic therapy during ablation. He was also on the
writing committee for the 2010 ESC Guidelines on Atrial Fibrillation
and was Deputy Editor for the 9th ACCP guidelines 
on antithrombotic therapy for AF.Professor Lip is involved at senior editorial level for several major
international journals, including Journal of Human Hypertension (Editor-in-
Chief), Thrombosis and Haemostasis (Editor-in-Chief [Clinical Studies]
designate), Thrombosis Research (Associate Editor), Europace (Associate
Editor), and Circulation (Guest Editor). He has published and lectured
extensively on thrombosis and antithrombotic disease in cardiovascular
disease.

Dr Eduard Shantsila is a Postdoctorate Research Fellow at the University
of Birmingham Centre for Cardiovascular Science, City Hospital,
Birmingham, UK, where he leads a research group working on a number
of research projects that investigate endothelial damage/recovery and
monocyte characteristics including their role in thrombosis in patients with
acute coronary syndromes, heart failure, and systemic atherosclerosis.
Dr Shantsila worked in the Republican Research and Practical Centre
‘Cardiology,’ Minsk, Belarus, as a researcher and a cardiologist from 1998
and completed his PhD thesis in 2002 in Minsk, Belarus and another
PhD thesis in 2012 in Birmingham, United Kingdom. From 2005 to 2008
he was a head of the Department of Urgent Cardiology in this centre,
where he was actively involved in research work on the problems of cardiovascular diagnostics, endothelial dysfunction, and thrombosis. He is
a member of the Working Group of Thrombosis of the ESC. Dr Shantsila
has published extensively on these topics, and is a peer reviewer of major
journals in thrombosis.

Bibliographic Information

  • Book Title: Non-Vitamin K Antagonist Oral Anticoagulants

  • Book Subtitle: A Concise Guide

  • Authors: Eduard Shantsila, Gregory YH Lip

  • DOI: https://doi.org/10.1007/978-3-319-25460-9

  • Publisher: Adis Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and the Author(s) 2016

  • License: CC BY-NC

  • eBook ISBN: 978-3-319-25460-9

  • Edition Number: 1

  • Number of Pages: X, 50

  • Number of Illustrations: 6 b/w illustrations, 7 illustrations in colour

  • Topics: Hematology, Surgery, Cardiology