Brain Function and Responsiveness in Disorders of Consciousness

  • Martin M. Monti
  • Walter G. Sannita

Table of contents

  1. Front Matter
    Pages i-xi
  2. Lizette Heine, Steven Laureys, Caroline Schnakers
    Pages 25-36
  3. Carol Di Perri, Jitka Annen, Georgios Antonopoulos, Enrico Amico, Carlo Cavaliere, Steven Laureys
    Pages 51-65
  4. Adrian M. Owen, Lorina Naci
    Pages 67-80
  5. Silvia Casarotto, Mario Rosanova, Olivia Gosseries, Mélanie Boly, Marcello Massimini, Simone Sarasso
    Pages 93-104
  6. Damian Cruse, G. Bryan Young, Francesco Piccione, Marianna Cavinato, Aldo Ragazzoni
    Pages 105-118
  7. Back Matter
    Pages 205-207

About this book


This book provides up-to-date information on all aspects of brain function and responsiveness in patients with severe disorders of consciousness. Topics considered include the mechanisms and measures of consciousness; perfusional, metabolic, and fMRI markers of responsiveness; responsiveness to pain; the role of brain–computer interface techniques; electrophysiology; cortical excitability; autonomic responsiveness; the natural history of vegetative and minimally conscious states; and prediction of outcome. Brain neuroimaging has documented residual responsiveness in the vegetative state. The scientific impact of this seminal evidence has generated a schism between neuroscience and the clinical criteria defining consciousness and responsiveness. Our current understanding of human consciousness must be reconsidered also in view of the emotional impact on the public and the far-reaching implications for diagnosis, prognosis, medical treatment, human costs, medical and individual responsibility, logistics, healthcare, ethics, etc. It is hoped that this book will help to bridge the gap between neuroscience and clinical routine.


Brain injury Neuroimaging Neurorehabilitation Pain responsiveness Perfusion Vegetative state

Editors and affiliations

  • Martin M. Monti
    • 1
  • Walter G. Sannita
    • 2
  1. 1.Dept. of Psychology and NeurosurgeryUniversity of California, L.A.Los AngelesUSA
  2. 2.Dept of Neurosc, Ophthalmol and GeneticsUniversity of GenovaGenovaItaly

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-21424-5
  • Online ISBN 978-3-319-21425-2
  • Buy this book on publisher's site