© 2015

Resistance to Immunotoxins in Cancer Therapy

  • Rama Shanker Verma
  • Benjamin Bonavida

Part of the Resistance to Targeted Anti-Cancer Therapeutics book series (RTACT, volume 6)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Sudarshan Gadadhar, Anjali A. Karande
    Pages 1-31
  3. Sithambaram Devilakshmi, Jayaprakasam Madhumathi, Rama Shanker Verma
    Pages 33-56
  4. Sebastian Stahl, Fabian Mueller, Ira Pastan, Ulrich Brinkmann
    Pages 57-73
  5. Roland B. Walter
    Pages 75-87
  6. Christian Cremer, Grit Hehmann-Titt, Sonja Schiffer, Georg Melmer, Paolo Carloni, Stefan Barth et al.
    Pages 185-219
  7. Back Matter
    Pages 247-249

About this book


This volume is a guide to understanding resistance against targeted therapeutic approaches for cancer using immunotoxins. It contains a detailed review of the history and development of targeted therapy. As well, it includes an in-depth description of the molecular and cellular mechanisms involved in cancer resistance and several novel methods to overcome resistance. Each chapter discusses different aspects of resistance and covers all the factors that may contribute to resistance in cancer cells. Finally, this volume highlights the recent findings and advances associated with tackling cancer resistance.


antibodies chemoresistance drug development drug resistance immunotoxin resistance

Editors and affiliations

  • Rama Shanker Verma
    • 1
  • Benjamin Bonavida
    • 2
  1. 1.Department of BiotechnologyIndian Institute of Technology MadrasChennaiIndia
  2. 2.Department of Microbiology, Immunology,University of California of Los AngelesLos AngelesUSA

About the editors

Rama Shanker Verma, Ph.D., is Professor, Department of Biotechnology, the Indian Institute of Technology. Professor Verma specializes in the development of novel immunotoxins for cancer therapies. He has published 76 scientific articles, five book chapters, and several conference abstracts. He is an Elected Fellow, the Association of Microbiologists of India an Elected Fellow, the Society for Applied Biotechnology. He received the award for Excellence in Medical Biotechnology from the Society for Applied Biotechnology.

Bibliographic information

  • Book Title Resistance to Immunotoxins in Cancer Therapy
  • Editors Rama Shanker Verma
    Benjamin Bonavida
  • Series Title Resistance to Targeted Anti-Cancer Therapeutics
  • Series Abbreviated Title Resistance to Targeted Anti-Cancer Therapeutics
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2015
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-319-17274-3
  • Softcover ISBN 978-3-319-38456-6
  • eBook ISBN 978-3-319-17275-0
  • Series ISSN 2196-5501
  • Series E-ISSN 2196-551X
  • Edition Number 1
  • Number of Pages XVI, 249
  • Number of Illustrations 3 b/w illustrations, 19 illustrations in colour
  • Topics Cancer Research
    Drug Resistance
  • Buy this book on publisher's site