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  • Book
  • © 2015

Targeted Drug Delivery : Concepts and Design

Editors:

(view affiliations)
  • Comprehensively covers diverse aspects of drug targeting in a single volume

  • Examines advanced characterization techniques for nanocarriers

  • Sections devoted to toxicity issues and regulatory concerns, areas often overlooked

  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Delivery Science and Technology (ADST)

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eBook
USD 179.00
Price excludes VAT (USA)
  • ISBN: 978-3-319-11355-5
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD 229.99
Price excludes VAT (USA)
Hardcover Book
USD 279.99
Price excludes VAT (USA)

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-xviii
  2. Targeted Drug Delivery: Basic Concepts and Advances

    1. Front Matter

      Pages 1-1
    2. Targeted Drug Delivery Systems: Strategies and Challenges

      • Bhushan S. Pattni, Vladimir P. Torchilin
      Pages 3-38
  3. Disease-Based Targeting

    1. Front Matter

      Pages 39-39
    2. Recent Advances in Tumor Targeting Approaches

      • Kaushik Thanki, Varun Kushwah, Sanyog Jain
      Pages 41-112
    3. Infectious Diseases: Need for Targeted Drug Delivery

      • Padma V. Devarajan, Shilpa M. Dawre, Rinku Dutta
      Pages 113-148Open Access
  4. Organ-Based Targeting

    1. Front Matter

      Pages 149-149
    2. Image-Guided Delivery of Therapeutics to the Brain

      • Lipa Shah, Arun K. Iyer, Meghna Talekar, Mansoor M. Amiji
      Pages 151-177
    3. Inhalation Therapy for Pulmonary Tuberculosis

      • Keiji Hirota, Keishiro Tomoda, Kimiko Makino, Hiroshi Terada
      Pages 179-195
    4. Hepatic Targeting: Physiological Basis and Design Strategy

      • Anisha A. D’Souza, Vishvesh M. Joshi, Padma V. Devarajan
      Pages 197-238
  5. Cell- and Cell Organelle–Based Targeting

    1. Front Matter

      Pages 239-239
    2. Targeted Drug Delivery to the Mitochondria

      • Udita Agrawal, Rajeev Sharma, Suresh P. Vyas
      Pages 241-270
    3. Targeted Delivery of Nucleic Acid Therapeutics via Nonviral Vectors

      • Mamta Kapoor, Diane J. Burgess
      Pages 271-312
    4. Mucosal Vaccine Delivery and M Cell Targeting

      • Prem N. Gupta
      Pages 313-337
  6. Physicochemical Approaches for Targeting

    1. Front Matter

      Pages 339-339
    2. Stimuli Responsive Carriers: Magnetically, Thermally and pH Assisted Drug Delivery

      • Eameema Muntimadugu, Anjali Jain, Wahid Khan
      Pages 341-365
    3. Prodrug Conjugate Strategies in Targeted Anticancer Drug Delivery Systems

      • Shashwat Banerjee, Kiran Todkar, Govind Chate, Jayant Khandare
      Pages 367-387
    4. Polymer–Drug Conjugates for Targeted Drug Delivery

      • Anjan Kumar Mohanty, Fahima Dilnawaz, Guru Prasad Mohanta, Sanjeeb Kumar Sahoo
      Pages 389-407
  7. Carrier-Based Approaches for Targeted Drug Delivery

    1. Front Matter

      Pages 409-409
    2. Functionalized Lipid Particulates in Targeted Drug Delivery

      • Mangal S. Nagarsenker, Ankitkumar S. Jain, Sanket M. Shah
      Pages 411-431

About this book

This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

Keywords

  • lipidic carriers
  • micelles
  • nanocarriers
  • nanoparticles
  • polymeric
  • prodrugs

Editors and Affiliations

  • Institute of Chemical Technology, Department of Pharmaceutical Sciences and Technology, Mumbai, India

    Padma V. Devarajan

  • National Institute of Pharmaceutical Education and Research (NIPER), Centre for Pharmaceutical Nanotechnology, Department of Pharmaceutics, Mohali, India

    Sanyog Jain

About the editors

Prof. Padma V. Devarajan is Professor in Pharmacy and Head of the Department of Pharmaceutical Sciences and Technology at the Institute of Chemical Technology (ICT), Mumbai, India. She obtained her PhD (Tech) in pharmaceutics from the Department of Chemical Technology, University of Mumbai, India. Her research interests include nanocarriers for targeted delivery in cancer and infectious diseases, scale-up of nano drug delivery systems (DDS), bioenhancement strategies, and mucosal DDS as alternatives to parenteral administration for protein and nucleic acid delivery. Prof. Devarajan has supervised more than one hundred master’s and doctoral candidates. Her research is funded by the government of India and the national and international pharmaceutical industry. She is an author of several book chapters and has publications in peer-reviewed high impact journals. She has a number of granted patents, with four licensed to the industry. Prof. Devarajan has served as board member, member on the Board of Scientific Advisors and Chair of the Young Scientist Mentor Protégé Sub-committee of the Controlled Release Society. She is a recipient of the American Association of Indian Pharmaceutical Scientists (AAiPS) Distinguished Educator and Researcher Award, the VASVIK award for Industrial Research to Women, and the Association of Pharmaceutical Teachers of India–C.J. Shishoo Award for Research in Pharmaceutical Sciences, and she is a nominated Fellow of the Maharashtra Academy of Sciences, India.

 

Dr. Sanyog Jain is currently Assistant Professor at the Centre for Pharmaceutical Nanotechnology, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Mohali (Punjab), India. He obtained his Ph.D. in pharmaceutics from Dr. Hari Singh Gour University, Sagar (MP), India. His key research interests include exploring nano drug delivery systems for various biomedical applications including targeted anticancer drug delivery, oral delivery of vaccines, peptides and therapeutics, topical and transdermal drug delivery, gene delivery and carbon nanotubes. He has patented several nanotechnology based drug delivery platforms and licensed Tamoxifen-SEDDS Technology for improved breast cancer therapy to industry for commercialization. He has authored several book chapters and published research papers in high impact journals. Dr. Jain has won several prestigious awards including Bharat Jyoti (The Glory of India) Award, Alkyl Amine Young Scientist Award, Indian National Science Academy (INSA) Medal for Young Scientists, OPPI Young Scientist Award and Punjab State Young Scientist Award for outstanding research in the field of drug delivery systems. He has supervised more than fifty master’s and doctoral students and a post doc. His research is well funded by various government agencies and pharmaceutical industries. Jain is a widely travelled scientist and has delivered invited talks at numerous prestigious platforms.

Bibliographic Information

  • Book Title: Targeted Drug Delivery : Concepts and Design

  • Editors: Padma V. Devarajan, Sanyog Jain

  • Series Title: Advances in Delivery Science and Technology

  • DOI: https://doi.org/10.1007/978-3-319-11355-5

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Controlled Release Society 2015

  • Hardcover ISBN: 978-3-319-11354-8

  • Softcover ISBN: 978-3-319-37625-7

  • eBook ISBN: 978-3-319-11355-5

  • Series ISSN: 2192-6204

  • Series E-ISSN: 2192-6212

  • Edition Number: 1

  • Number of Pages: XVIII, 790

  • Number of Illustrations: 22 b/w illustrations, 103 illustrations in colour

  • Topics: Pharmaceutics

Buying options

eBook
USD 179.00
Price excludes VAT (USA)
  • ISBN: 978-3-319-11355-5
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD 229.99
Price excludes VAT (USA)
Hardcover Book
USD 279.99
Price excludes VAT (USA)