Liver Immunology

Principles and Practice

  • M. Eric Gershwin
  • John M. Vierling
  • Michael P. Manns

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Ian R. Mackay
    Pages 1-9
  3. Cliona O’Farrelly, Derek Doherty
    Pages 11-26
  4. Carlo Selmi, Cecilia B. Chighizola, Angela Ceribelli, Maria De Santis, Pier Luigi Meroni, Renqian Zhong
    Pages 27-43
  5. Christopher L. Bowlus
    Pages 45-53
  6. Percy A. Knolle
    Pages 55-64
  7. Mathias Heikenwalder, Percy Knolle, Ulrike Protzer
    Pages 65-77
  8. Zhigang Tian, Cai Zhang, Zhe-Xiong Lian
    Pages 79-94
  9. Eirini I. Rigopoulou, Daniel S. Smyk, Timoklia Orfanidou, Dimitrios P. Bogdanos, M. Eric Gershwin
    Pages 123-144
  10. Shyamapada Mandal, Manisha Mandal
    Pages 145-158
  11. Gadi Lalazar, Yaron Ilan
    Pages 159-171
  12. Rosa M. Pintó, Albert Bosch, Gerardo Kaplan
    Pages 173-189
  13. Mario U. Mondelli, Stefania Varchetta, Francesco Negro
    Pages 207-230
  14. Sebastian Lunemann, Jan Grabowski, Heiner Wedemeyer
    Pages 231-241
  15. Hiroki Takahashi, Mikio Zeniya
    Pages 243-252
  16. Pietro Invernizzi, Patrick S. C. Leung, Xiong Ma, M. Eric Gershwin
    Pages 253-279
  17. Diego Vergani, Rodrigo Liberal, Giorgina Mieli-Vergani
    Pages 281-300

About this book


Liver Immunology: Principles and Practice, Second Edition begins with important information about the epidemiology and mortality of liver disease worldwide. This information is followed by chapters related to basic immunology, application of liver immunology for diagnosis, and several excellent chapters that provide a solid foundation for understanding immune-mediated liver disease, including those associated with the biliary tree. A chapter on non-hepatic manifestations of immune mediated liver disease helps provide context for how these diseases affect the patient overall.  In addition, chapters discuss various discrete immunologically-mediated infectious liver disorders including those related to bacteria, parasites, and all of the classic viruses. Chapters on the traditional autoimmune liver diseases --  primary biliary cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis as well as overlap syndrome – are also included. The breadth of this comprehensive second edition is highlighted by chapters on alcoholic liver disease, non-alcoholic fatty liver disease, and drug-induced liver disease, among others.  This invaluable new edition ends with a forward-looking view of future directions and how the field might meet the challenge of refractory patients.  Developed by a renowned group of authors, Liver Immunology: Principles and Practice, Second Edition will again serve as a comprehensive textbook by providing an excellent overview for this rapidly evolving field. It greatly adds to the understanding of the pathogenesis of these diseases, while also providing novel insights that can be harnessed into helping improve the care of patients afflicted with various immune-mediated diseases.  This volume will again be a must-read for clinicians at all levels, investigators and students.

Editors and affiliations

  • M. Eric Gershwin
    • 1
  • John M. Vierling
    • 2
  • Michael P. Manns
    • 3
  1. 1.Division of Rheumatology, Allergy and Clinical ImmunologyUniversity of California School of MedicineDavisUSA
  2. 2.Medicine and SurgeryBaylor College of MedicineHoustonUSA
  3. 3.Department of Gastroenterology, Hepatology and EndocrinologyMedical School of HannoverGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, New York 2014
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-02095-2
  • Online ISBN 978-3-319-02096-9
  • About this book