Function and Regulation of Cellular Systems

  • Andreas Deutsch
  • Jonathon Howard
  • Martin Falcke
  • Walter Zimmermann

Part of the Mathematics and Biosciences in Interaction book series (MBI)

Table of contents

  1. Front Matter
    Pages i-x
  2. Metabolic Networks and Engineering

    1. Front Matter
      Pages 1-1
    2. Reinhart Heinrich, Thomas Höfer
      Pages 3-5
    3. Finn Hynne, Sune Danø, Preben G. Sørensen
      Pages 7-18
    4. Jochen Förster, Mats Åkesson, Jens Nielsen
      Pages 47-58
  3. Intracellular Signal Transduction

    1. Front Matter
      Pages 59-59
    2. Thomas Höfer, Reinhart Heinrich
      Pages 61-62
    3. Michael Meyer-Hermann, Frido Erler, Gerhard Soff
      Pages 63-71
    4. Birgit Schöberl, Martin Ginkel, Ernst D. Gilles, Gertrud Müller
      Pages 73-87
    5. Paramita Ghosh, Debasish Bose, Subhendu Ghosh
      Pages 89-97
    6. Antonio Politi, Thomas Höfer
      Pages 99-110
  4. Cellular Materials: Mechanics and Motility

    1. Front Matter
      Pages 133-133
    2. Erwin Frey, Wolfgang Alt
      Pages 135-137
    3. Chris H. Wiggins, Loïc Le Goff
      Pages 139-150
    4. Andrea Parmeggiani, Christoph F. Schmidt
      Pages 151-176
    5. Wolfgang Pompe, Katharina Flade, Michael Gelinsky, Birgit Knepper-Nicolai, Antje Reinstorf
      Pages 177-183

About this book


Current biological research demands more and more the extensive use of sophisticated mathematical methods and computer-aided analysis of experiments and data. Mathematical analysis reveals similarities and differences in organization principles of metabolic, signaling and cellular interaction networks.
This highly interdisciplinary book focuses on structural, dynamical and functional aspects of cellular systems and presents corresponding experiments and mathematical models. It may serve as an introduction for biologists, mathematicians and physicists to key questions in cellular systems which can be studied with mathematical models. Recent model approaches are presented with applications in cellular metabolism, intra- and intercellular signaling, cellular mechanics, network dynamics and pattern formation. In addition, applied issues as tumor cell growth, dynamics of the immune system and biotechnology are included. The book is based on selected peer-reviewed contributions and discussions at the "1. International MTBio workshop on function and regulation of cellular systems: experiments and models" (Dresden, June 24-30, 2001). The international competence and information network MTBio (Modeling and Theory in the Biosciences, has been recently founded to improve communication between experimentalists and theoreticians sharing interests in the application of mathematical models.


Computerassistierte Detektion Dynamics Gap Hydra Immune System In silico Radiologieinformationssystem migration model modeling nonlinear dynamics regulation simulation system

Editors and affiliations

  • Andreas Deutsch
    • 1
  • Jonathon Howard
    • 2
  • Martin Falcke
    • 3
  • Walter Zimmermann
    • 4
  1. 1.Zentrum für HochleistungsrechnenTechnische Universität DresdenDresdenGermany
  2. 2.Max Planck Institute of Molecular Cell Biology and GeneticsDresdenGermany
  3. 3.Department Theory (SF5)Hahn-Meitner-Institut BerlinBerlinGermany
  4. 4.Theoretische PhysikUniversität des SaarlandesSaarbrückenGermany

Bibliographic information

  • DOI
  • Copyright Information Birkhäuser Basel 2004
  • Publisher Name Birkhäuser, Basel
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-0348-9614-6
  • Online ISBN 978-3-0348-7895-1
  • About this book