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Infection, Immune Homeostasis and Immune Privilege

  • Joan Stein-Streilein

Part of the Birkhäuser Advances in Infectious Diseases book series (BAID)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Linda D. Hazlett, Joan Stein-Streilein
    Pages 1-29
  3. Dirk Wohlleber, Percy A. Knolle
    Pages 93-106
  4. Ya-Jen Chang, Rosemarie H. DeKruyff, Dale T. Umetsu
    Pages 107-124
  5. Joanna Wroblewska, Cathryn Nagler
    Pages 125-147
  6. Back Matter
    Pages 149-153

About this book

Introduction

Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated “immune-privileged sites” by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms.

This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.

Keywords

immune homeostasis immune privilege inflammation

Editors and affiliations

  • Joan Stein-Streilein
    • 1
  1. 1., Department of OphthalmologySchepens Eye Research InstituteBostonUSA

Bibliographic information