Overview
Contains the latest information on the development of pharmacoresistance in epilepsy
Discusses novel therapeutic strategies to counteract the development of pharmacoresistance
Presents new strategies to prevent or reduce the progression of the disease
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Table of contents (26 chapters)
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Front Matter
Keywords
About this book
This new edition of Pharmacoresistance in Epilepsy addresses all issues relating to drug-resistance in epilepsy, including studies in patients as well in experimental models and presents the basis for an understanding of recent developments in the pathogenesis and treatment of this condition. Important issues associated with drug-resistant epilepsy are reviewed and updated, such as abnormalities in inhibitory mechanisms, neurotoxicity and changes the immune system associated with this disorder, and the development of drug-resistance as consequence of chronic exposure to antiseizure-medications. Considering that a major obstacle is that epilepsy associated with drug-resistance cannot be controlled with the traditional antiseizure medications, specific chapters describe therapeutic strategies to prevent or reduce the progression of the disease with complementary medical therapies, such as transcranial focal stimulation to promote neuroprotection. Pharmacoresistance in Epilepsy is a valuable resource for anyone working in the field, whether studying epilepsy in the lab or treating it in an office.
Editors and Affiliations
About the editors
Luisa Rocha is Professor in the Department of Pharmacobiology of the Center for Research and Advanced Studies in Mexico City, Mexico.
Esper Cavalheiro is Professor Emeritus at the Universidade Federal de Sao Paulo/Escola Paulista de Medicina, Brasil.
Alberto Lazarowski is Full Professor at Universidad de Buenos Aires, Argentina.
Bibliographic Information
Book Title: Pharmacoresistance in Epilepsy
Book Subtitle: From Genes and Molecules to Promising Therapies
Editors: Luisa L. Rocha, Alberto Lazarowski, Esper A. Cavalheiro
DOI: https://doi.org/10.1007/978-3-031-36526-3
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023
Hardcover ISBN: 978-3-031-36525-6Published: 30 August 2023
Softcover ISBN: 978-3-031-36528-7Due: 13 September 2024
eBook ISBN: 978-3-031-36526-3Published: 29 August 2023
Edition Number: 2
Number of Pages: XV, 596
Number of Illustrations: 5 b/w illustrations, 79 illustrations in colour
Topics: Neurosciences, Neurology, Pharmacology/Toxicology