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Molecular Imaging and Targeted Therapy

Radiopharmaceuticals and Clinical Applications

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  • © 2023
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  • Reviews radioisotope-based molecular imaging probes (radiopharmaceuticals) for PET and SPECT
  • Covers basics of nuclear chemistry, radiochemistry and radiopharmacology
  • Discusses potential applications in drug development, translational medicine and clinical diagnostics

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About this book

This book, now published in its second edition, covers a wide range of topics relating to the use of radiopharmaceuticals. The basics of nuclear chemistry, radiochemistry, and radiopharmacology are considered in detail, regulatory issues are reviewed, and potential applications in drug development, translational medicine, clinical diagnostics, and targeted therapy are discussed. Compared with the first edition, the chapters on targeted therapy with alpha- and beta-emitting radiopharmaceuticals and theranostics are completely new. Other chapters have been updated and revised as necessary.

Radioisotope-based molecular imaging probes (radiopharmaceuticals) provide unprecedented insights into biochemistry and function in both normal and diseased states of living systems, with unbiased in vivo measurements of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology, including functional magnetic resonance imaging, can provide such high sensitivity and specificity at a tracer level. This book, written by an experienced radiochemist and scientist, offers valuable insights into the full range of applications of this technology.

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Table of contents (22 chapters)

Authors and Affiliations

  • Professor Emeritus of Radiochemistry and Radiopharmacy in Radiology, Weill Cornell Medicine, Cornell University, New York, USA

    Shankar Vallabhajosula

About the author

Dr. Vallabhajosula attended high school in the small town of Bobbili, Andhra Pradesh, India. He graduated from Andhra University with a BS and MS in Pharmacy and subsequently obtained his Ph.D. from the University of Southern California, in 1980. After receiving the doctorate, he first worked at Mount Sinai Medical Center in New York and since 1997 has been a Professor of Radiochemistry and Radiopharmacy in Radiology at Weill Cornell Medicine of Cornell University and New York Presbyterian Hospital. He is now the Professor Emeritus in Radiology at Weill Cornell Medicine. 

Bibliographic Information

  • Book Title: Molecular Imaging and Targeted Therapy

  • Book Subtitle: Radiopharmaceuticals and Clinical Applications

  • Authors: Shankar Vallabhajosula

  • DOI:

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2023

  • Hardcover ISBN: 978-3-031-23203-9Published: 01 April 2023

  • eBook ISBN: 978-3-031-23205-3Published: 31 March 2023

  • Edition Number: 2

  • Number of Pages: XXV, 708

  • Number of Illustrations: 62 b/w illustrations, 306 illustrations in colour

  • Topics: Nuclear Medicine, Oncology, Neurology

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