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Biotechnologies for Gene Therapy

RNA, CRISPR, Nanobots, and Preclinical Applications

  • Addresses the delivery microRNA and CRISPR for a variety of diseases, including cancer and cardiovascular disease

  • Illustrates the delivery methods and techniques for preclinical applications of miroRNA and CRISPR gene therapy

  • Identifies biotechnologies for gene therapy that have the potential for developing into new clinical therapies

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • ISBN: 978-3-030-93333-3
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Hardcover Book USD 169.99
Price excludes VAT (USA)

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-ix
  2. Small Activating RNA Therapy for Angiogenesis

    • Pia Laitinen, Tiia A. Turunen, Mikko P. Turunen
    Pages 45-59
  3. Muscular Dystrophy Therapy Using Viral Vector-based CRISPR/Cas

    • Eunyoung Choi, Taeyoung Koo
    Pages 61-83
  4. CRISPR-Cas-Based Gene Therapy to Target Viral Infections

    • Mouraya Hussein, Ben Berkhout, Elena Herrera-Carrillo
    Pages 85-125
  5. CRISPR Targeting the Integrated HTLV-1 Virus

    • Tasha Wilkie, Amanda R. Panfil
    Pages 127-144
  6. Retroviral Vectors for Gene Therapy of Monogenic Diseases

    • Kristine E. Yoder, Anthony J. Rabe, Ross C. Larue
    Pages 145-159
  7. DNA Origami Nanodevices for Therapeutic Delivery Applications

    • Patrick D. Halley, Christopher R. Lucas, NikÅ¡a Roki, Nicholas J. Vantangoli, Kurtis P. Chenoweth, Carlos E. Castro
    Pages 161-194
  8. Back Matter

    Pages 195-203

About this book

The purpose of this book is to highlight some of latest developments and applications of CRISPR, RNA, and DNA to treat diseases ranging from cancers to cardiovascular and degenerative disorders. It also features innovations of the delivery methods for nucleic acids ranging from nanodevices made from DNA and pseudo amino acids to viral vectors. This is an ideal book for academics, clinicians, and students interested in gene therapy.

Keywords

  • DNA nanobots
  • CRISPR gene therapy
  • microRNA gene therapy
  • DNA gene therapy
  • delivery microRNA
  • clinical applications RNA molecules
  • clinical applications DNA nanobots

Editors and Affiliations

  • Department of Biomedical Engineering, College of Engineering and Polymer Science, The University of Akron, Akron, USA

    Yang H. Yun

  • Department of Cancer Biology and Genetics College of Medicine, The Ohio State University, Columbus, USA

    Kristine E. Yoder

About the editors

Dr. Yang Yun is an Associate Professor in the Biomedical Engineering Department at the University of Akron. His research interested include biomaterials, cancer therapy, drug and gene delivery, electrospinning, nanotechnology, tissue engineering, and the treatment of infectious diseases.

Dr. Kristine Yoder is  an Associate Professor in the department of Cancer Biology and Genetics at Ohio State University.

Bibliographic Information

  • Book Title: Biotechnologies for Gene Therapy

  • Book Subtitle: RNA, CRISPR, Nanobots, and Preclinical Applications

  • Editors: Yang H. Yun, Kristine E. Yoder

  • DOI: https://doi.org/10.1007/978-3-030-93333-3

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-030-93332-6Published: 03 June 2022

  • Softcover ISBN: 978-3-030-93335-7Due: 17 June 2023

  • eBook ISBN: 978-3-030-93333-3Published: 02 June 2022

  • Edition Number: 1

  • Number of Pages: IX, 203

  • Number of Illustrations: 3 b/w illustrations, 23 illustrations in colour

  • Topics: Medical Genetics, Biomedical Engineering and Bioengineering, Biotechnology, Pharmaceutics

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • ISBN: 978-3-030-93333-3
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Hardcover Book USD 169.99
Price excludes VAT (USA)