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Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems

  • Book
  • © 2022

Overview

Editors:
  1. Jayvadan K. Patel

    1. Nootan Pharmacy College, Faculty of Pharmacy, Sankalchand Patel University, Visnagar, India

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    You can also search for this editor in PubMed   Google Scholar

  2. Yashwant V. Pathak

    1. College of Pharmacy, University of South Florida Health, Tampa, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Only consolidated reference that addresses PK/PD and nanocarriers
  • Presents an overview of biodistribution
  • Discusses the advantages of nanoparticle drug delivery systems (NPDDS)

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Part I

    1. Front Matter

      Pages 1-1
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    2. Introduction to Nanoparticulate Drug Delivery Systems

      • Jayvadan Patel, Anita Patel, Mukesh Patel, Govind Vyas
      Pages 3-23

    3. Nanoparticle Properties Affecting the Drug Release, Absorption, and Pharmacokinetics of Nanoparticulate Drug Delivery Systems

      • Prachi Pandey, Jayvadan K. Patel, Samarth Kumar
      Pages 25-40

    4. Models Used for Biopharmaceutical Evaluation of Nanoparticulate Drug Delivery System (NPDDS)

      • Seema Kohli, Sumeet Dwivedi
      Pages 41-51

    5. Models Used for Pharmacokinetic Evaluation of Nanoparticulate Drug Delivery Systems (NPDDS)

      • Nishtha Chaurawal, Kaisar Raza
      Pages 53-67

    6. Models Used in Pharmacodynamic Evaluation of Nanoparticulate Drug Delivery Systems (NPDDS)

      • Megha Joshi, Chander Parkash Dora, Lokesh Kaushik, Jayvadan Patel, Kaisar Raza
      Pages 69-77

    7. Preclinical Animal Models for the Experimental Design of Pharmacokinetic Studies with Nanoparticulate Drug Delivery Systems

      • Aaishwarya Deshmukh, Jayvadan K. Patel, Yashwant V. Pathak
      Pages 79-100

    8. Pharmacokinetic Modeling Program (PKMP): A Software for PK/PD Data Analysis

      • Ajit K. Shah
      Pages 101-139

  3. Part II

    1. Front Matter

      Pages 141-141
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    2. Pharmacokinetics and Pharmacodynamics of Liposomal Nanoparticles

      • Prachi Pandey, Jayvadan Patel, Samarth Kumar, Yashwant Pathak
      Pages 143-158

    3. Pharmacokinetics of Drug-in-Polymer Matrix-Based Nanoparticulate Drug Delivery System

      • Sopan Nangare, Prashant Patil, Ashwini Patil, Prashant Deshmukh, Trupti Powar, Jidnyasa Pantwalawalkar et al.
      Pages 159-186

    4. Pharmacokinetics of Long Circulating Inorganic Nanoparticulate Drug Delivery Systems

      • Namrata Gautam, Anushka Kulkarni, Debopriya Dutta, Sushama Talegaonkar
      Pages 187-208

    5. Metallic Gold Nanoparticles: In Vivo Pharmacokinetics and X-Ray Contrast Imaging Studies

      • Nishith Patel, Sunita Chaudhary, Jayvadan K. Patel
      Pages 209-223

    6. Mucoadhesive Nanoparticulate Drug Delivery System (NPDDS): In Vitro and Pharmacokinetic Studies

      • Sanjay Patil, Bhavin Choradiya, Jayvadan Patel
      Pages 225-243

    7. Pharmacokinetic and Tissue Distribution Study of Solid Lipid Nanoparticles

      • Himanshu Paliwal, Bhupendra G. Prajapati, Dignesh Khunt, Chilakapalli Shirisha, Jayvadan K. Patel, Yashwant V. Pathak
      Pages 245-260

    8. Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

      • Komal Parmar, Jayvadan Patel, Yashwant Pathak
      Pages 261-272

    9. PKPD of PLGA-PEG-PLGA Copolymeric Micelles

      • Shirleen Miriam Marques, Lalit Kumar
      Pages 273-292

  4. Part III

    1. Front Matter

      Pages 293-293
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    2. Bridging Bio-Nanoscience and Cancer Nanomedicine

      • Alka, Raquibun Nisha, Priya Singh, Ravi Raj Pal, Neelu Singh, Nidhi Mishra et al.
      Pages 295-313
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Keywords

About this book

A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems. No other consolidated published reference discusses the PK/PD study of nanoparticle drug delivery systems. This book discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not easily metabolized or that obtain the desired therapeutic effect with minimum toxicity.  The authors provide an overview of biodistribution with a focus on polymer and lipid nanoparticles.  

This thorough reference is divided into three parts: Modelling, Specific carries and their potential to treat specific diseases.

Editors and Affiliations

  • Nootan Pharmacy College, Faculty of Pharmacy, Sankalchand Patel University, Visnagar, India

    Jayvadan K. Patel

  • College of Pharmacy, University of South Florida Health, Tampa, USA

    Yashwant V. Pathak

About the editors

Dr. Jayvadan Patel is a Professor of Pharmaceutics and Principal, Nootan Pharmacy College and Dean (Faculty of Pharmacy), Sankalchand Patel University, Visnagar, Gujarat, India. He has more than 25 years of academic and research experience, has published more than 230 research and review papers in international and national Journals. Dr. Patel is an author of 15 books and 65 book chapters. Dr. Patel has guided 45 PhD; 104 M Pharm students for dissertation work. Dr. Patel is recipient of several awards including, very prestigious “AICTE-Visvesvaraya Best Teachers Award-2020” by All India Council for Technical Education, Government of India and “APTI Young Pharmacy Teacher Award-2014” by Association of Pharmaceutical Teachers of India. He is serving as Peer reviewers of 58 well reputed journals. Dr. Patel is serving as an Associate editor/member editorial board of 15 journals.



Prof. Yashwant Pathak, M.S., Ph.D. in Pharmaceutical Technologyfrom Nagpur University, India and EMBA and MS in Conflict Management from Sullivan University, KY, USA. He is the Associate Dean for Faculty Affairs at the College of Pharmacy, University of South Florida. Tampa, Florida. With extensive experience in academia as well as industry, he has to his credit more than 100 publications and 2 patents, including 5 books in Nanotechnology and 2 in Nutraceuticals and several books in cultural studies. He is also the Coordinator for the International Center for Cultural Studies, and is on the board of many organizations.

Bibliographic Information

  • Book Title: Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems

  • Editors: Jayvadan K. Patel, Yashwant V. Pathak

  • DOI: https://doi.org/10.1007/978-3-030-83395-4

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-030-83394-7Published: 08 March 2022

  • Softcover ISBN: 978-3-030-83397-8Published: 09 March 2023

  • eBook ISBN: 978-3-030-83395-4Published: 07 March 2022

  • Edition Number: 1

  • Number of Pages: XIII, 438

  • Number of Illustrations: 18 b/w illustrations, 84 illustrations in colour

  • Topics: Biotechnology, Medicinal Chemistry, Pharmaceutical Sciences/Technology, Pharmacology/Toxicology

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