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Fungal Extracellular Vesicles

Biological Roles

  • Presents the various functions of extracellular vesicles in fundamental biological processes
  • First book dedicated to fungal extracellular vesicles
  • Discusses applications of extracellular vesicle research in biomedicine

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 432)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xxix
  2. Biogenesis of Fungal Extracellular Vesicles: What Do We Know?

    • Haroldo C. de Oliveira, Amanda F. Kato, Bianca A. G. Sena, Iraine Duarte, Luísa J. Jozefowicz, Rafael F. Castelli et al.
    Pages 1-11
  3. Lessons Learned from Studying Histoplasma capsulatum Extracellular Vesicles

    • Daniel Zamith-Miranda, Lysangela Ronalte Alves, Ernesto Satoshi Nakayasu, Joshua Daniel Nosanchuk
    Pages 13-18
  4. Extracellular Vesicles from Sporothrix Yeast Cells

    • Marcelo Augusto Kazuo Ikeda, Karen Spadari Ferreira
    Pages 35-44
  5. Filamentous Fungi Extracellular Vesicles

    • Teresa Gonçalves, Joana Oliveira, Chantal Fernandes
    Pages 45-55
  6. Fungal Extracellular Vesicles in Interkingdom Communication

    • Maria Makarova, Robin C. May
    Pages 81-88
  7. Interactions of Extracellular Vesicles from Pathogenic Fungi with Innate Leukocytes

    • Mateus Silveira Freitas, Andre Moreira Pessoni, Carolina Coelho, Vânia Luiza Deperon Bonato, Marcio L. Rodrigues, Arturo Casadevall et al.
    Pages 89-120
  8. Fungal Extracellular Vesicles as a Potential Strategy for Vaccine Development

    • Leandro Honorato, Jhon Jhamilton Artunduaga Bonilla, Alicia C. Piffer, Leonardo Nimrichter
    Pages 121-138
  9. Current Microscopy Strategies to Image Fungal Vesicles: From the Intracellular Trafficking and Secretion to the Inner Structure of Isolated Vesicles

    • Camila Wendt, Vânia Vieira, Adélia Lima, Ingrid Augusto, Fernando P. de Almeida, Ana Paula R. Gadelha et al.
    Pages 139-159
  10. Proteomic Characterization of EVs in Non-pathogenic Yeast Cells

    • Pilar Morales, Ana Mencher, Jordi Tronchoni, Ramon Gonzalez
    Pages 161-170

About this book

This book provides an in-depth overview on the manifold functions of fungal extracellular vesicles (EV) which span from cell-to-cell communication, pathogenicity and stimulation of host’s immunity to export of hundreds of biomolecules. The book summarizes the present knowledge on the impact of extracellular vesicles on fungal biology. Extracellular vesicles participate in fundamental biological processes in all living cells but only during the last 15 years the production and functions of EVs were identified and studied in fungal species too. Up to date more than 50 independent studies have shown that extracellular vesicles are produced by at least 20 fungal species. 

The book addresses researchers and advanced students in Microbiology, Mycology and Biotechnology. 


Editors and Affiliations

  • Instituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz), Curitiba, Brazil

    Marcio Rodrigues

  • Département de Mycologie, Institut Pasteur, Paris, France

    Guilhem Janbon

About the editors

Marcio Rodrigues is a senior investigator at the Carlos Chagas Institute (Oswaldo Cruz Foundation, Fiocruz; Brazil). His laboratory is mainly interested in the mechanisms by which fungal cells export biologically active molecules to the extracellular space. In collaboration with Drs. Arturo Casadevall, Leonardo Nimrichter and Kildare Miranda, all authors in this volume, Marcio Rodrigues led the discovery of fungal extracellular vesicles in 2007.  His laboratory has been investigating the role of extracellular vesicles in fungal physiology and pathogenesis for the last decade, mainly using the Cryptococcus model of secretion. The group is especially interested in how lipids and glycans participate in secretory processes that are essential for fungi, aiming to connect basic cell biology mechanisms with the identification of cellular pathways that could be targeted by novel antifungal agents.


Guilhem Janbon is the head of the Unit RNA Biology in Fungal Pathogens and the director of the Department of Mycology of the Institute Pasteur in Paris (France). He has very long experience working and publishing papers dealing with different aspects of pathogenic or non-pathogenic fungi. His laboratory study different aspect of the RNA biology of some pathogenic fungi. His group is also interested in the analysis of the structure and genetics of fungal EVs. Since recently, in collaboration with Drs. Marcio Rodrigues and R May, his laboratory has been using the most updated technologies to revisit fungal EV structure and to study their diversity of shape, size and structure. 


Bibliographic Information

  • Book Title: Fungal Extracellular Vesicles

  • Book Subtitle: Biological Roles

  • Editors: Marcio Rodrigues, Guilhem Janbon

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-030-83391-6

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2021

  • Hardcover ISBN: 978-3-030-83390-9Published: 08 December 2021

  • Softcover ISBN: 978-3-030-83393-0Published: 09 December 2022

  • eBook ISBN: 978-3-030-83391-6Published: 01 January 2022

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: XXIX, 170

  • Number of Illustrations: 1 b/w illustrations

  • Topics: Mycology, Applied Microbiology, Eukaryotic Microbiology

Buy it now

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access