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  • © 2022

Environmental Alteration Leads to Human Disease

A Planetary Health Approach


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  • Explores the effects of ecological alterations on human health

  • Outlines a true interrelation between Medicine and advanced Ecology

  • Discusses the new correlation between the biological efficiency of a landscape unit and human health

Part of the book series: Sustainable Development Goals Series (SDGS)

  • 2012 Accesses

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  • ISBN: 978-3-030-83160-8
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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xiv
  2. Understanding Complexity in Life Sciences

    • Marta Bertolaso
    Pages 1-13
  3. A New Paradigm in Medicine: Psychoneuroendocrineimmunology and Science of Integrated Care

    • Anna Giulia Bottaccioli, Francesco Bottaccioli
    Pages 15-29
  4. From General Ecology to Bionomics

    • Vittorio Ingegnoli, Elena Giglio
    Pages 31-66
  5. Planetary Health: Human Impacts on the Environment

    • Vittorio Ingegnoli, Elena Giglio
    Pages 67-94
  6. Landscape Bionomics Dysfunctions and Human Health

    • Vittorio Ingegnoli
    Pages 95-130
  7. Agrofood System and Human Health

    • Stefano Bocchi, Simone Villa, Francesca Orlando, Ludovico Grimoldi, Mario Raviglione
    Pages 131-163
  8. Zootechnical Systems, Ecological Dysfunctions and Human Health

    • Luigi Bonizzi, Francesco Campana, Alessio Soggiu
    Pages 175-194
  9. Environmental Pollution and Cardiorespiratory Diseases

    • Cristina Sestili, Domenico Barbato, Rosario A. Cocchiara, Angela Del Cimmuto, Giuseppe La Torre
    Pages 195-208
  10. The Impact of Environmental Alterations on Human Microbiota and Infectious Diseases

    • Barbato Domenico, De Paula Baer Alice, Lia Lorenza, Giada La Torre, Rosario A. Cocchiara, Cristina Sestili et al.
    Pages 209-227
  11. The Relationship Between Environment and Mental Health

    • Rosario A. Cocchiara, Alice Mannocci, Insa Backhaus, Domitilla Di Thiene, Cristina Sestili, Domenico Barbato et al.
    Pages 229-240
  12. Planetary Health and Healthcare Workers

    • Giuseppe La Torre, Barbara Dorelli, Alice De Paula Baer, Domenico Barbato, Lorenza Lia, Maria De Giusti
    Pages 241-260
  13. Endocrine Disruptors and Human Reproduction

    • Francesco Pallotti, Donatella Paoli, Francesco Lombardo
    Pages 261-274
  14. Environmental Factors in the Development of Diabetes Mellitus

    • Caterina Formichi, Andrea Trimarchi, Carla Maccora, Laura Nigi, Francesco Dotta
    Pages 275-317

About this book

This book aims to explore the impact of human alterations of Earth’s ecological systems on human health. Human activities are producing fundamental biophysical changes faster than ever before in the history of our species, which are accompanied by dangerous health effects. Drawing on advanced ecological principles, the book demonstrates the importance of using systemic medicine to study the effects of ecological alterations on human health.

Planetary Health is an interdisciplinary field, but first of all it must be systemic and it needs a preferential relationship between Ecology and Medicine. This relation is to be upgrading, because today both ecology and medicine pursue few systemic characters and few correct interrelations. We need to refer to new principles and methods sustained by the most advanced fields, as Landscape Bionomics and Systemic Medicine. Thus, we will be able to better discover environmental syndromes and their consequences on human health. Environmental transformations proposed by PHA (from biodiversity shifts to climate change) do not consider bionomic dysfunctions which can menace human health. On the contrary, finding advanced diagnostic criteria in landscape syndromes can strongly help to find the effects on human well-being. The passage from sick care to health care can’t avoid the mentioned upgrading.


  • SDG3
  • Wellbeing
  • Public Health
  • Global Health
  • Systemic Medicine
  • Ecology
  • Landscape Bionomics
  • PNEI (Psycho-Neuro-Endocrine-Immunology)

Editors and Affiliations

  • Environmental Science & Policy, University of Milan, Milano, Italy

    Vittorio Ingegnoli

  • Department of Experimental Medicine “Sapienza”, Laboratory of Seminology, Bank of Semen “Loredana Gandini”, University of Roma, Roma, Italy

    Francesco Lombardo

  • Public Health and Infectious Diseases, Sapienza University of Rome, Roma, Italy

    Giuseppe La Torre

About the editors

Vittorio Ingegnoli is the founder of the new discipline of Landscape Bionomics. Since 2016 he has been a Visiting Professor of Landscape Bionomics at the Dept. of Environmental Science & Policy at the University of Milan, Italy. His research focuses on environmental alterations in connection with human health. From 2004 to 2008 he was a Member of the Con. Eco. For. (CFS, State Foresters) and ICP European Forest Monitoring; from 2012 to 2014 he was Coordinator of the Research on Suburban Landscapes in Brussels and Milan, KU-Leuven, Belgium, with prof. H. Gulink. Currently, he is a Member of the Planetary Health Alliance (University of Harvard), of the SIPNEI (It. Soc. of Psycho-Neuro-Endocrine-Immunology) and of the Academic Experts for CAI Central Scientific Committee (It. Alpine Club). He has authored more than 150 books and articles.

Francesco Lombardo is a Visiting Professor at the Royal University of Jordan, Director of the Master in Andrology and Seminology of the University of Rome “La Sapienza,” and Member of the Ethical Committee of the University Hospital “Umberto I” of Rome since 2016. Since 1989 he has been involved in an Operative Unit of the “Prevention and Control of Diseases Factors” (FATMA) Subproject “Control of Human Fertility,” sponsored by the Italian National Council of Research. He is a member of various national and international societies (e.g. the Italian Society of Fertility and Sterility, the Italian Society of Endocrinology, the American Society for Reproductive Medicine, the International Society of Immunology of Reproduction). He has authored or co-authored more than 100 papers in national and international journals.               

Giuseppe La Torre is an Associate Professor of Occupational Medicine at Sapienza University of Rome, and Head of the Unit of Occupational Medicine of the Teaching Hospital Policlinico Umberto I in Rome. He has experience of teaching in Hygiene, Public Health, Epidemiology and Biostatistics (Catholic University Rome, University of Rome “La Sapienza,” University of Cassino). He has been head of the Epidemiology and Biostatistics Unit at the Catholic University of Rome, and was responsible for the Health Technology Assessment Public Health Unit at the Institute of Hygiene. The research activities are mainly focused on Occupational risk factors, Environment, Public Health and Prevention. He serves as Editor for several international scientific journals (e.g. Public Health, Journal of Public Health (Springer), Journal of Clinical Medicine, Vaccines, Clinica Terapeutica).

Bibliographic Information

  • Book Title: Environmental Alteration Leads to Human Disease

  • Book Subtitle: A Planetary Health Approach

  • Editors: Vittorio Ingegnoli, Francesco Lombardo, Giuseppe La Torre

  • Series Title: Sustainable Development Goals Series

  • DOI:

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-030-83159-2

  • eBook ISBN: 978-3-030-83160-8

  • Series ISSN: 2523-3084

  • Series E-ISSN: 2523-3092

  • Edition Number: 1

  • Number of Pages: XIV, 337

  • Number of Illustrations: 9 b/w illustrations, 85 illustrations in colour

  • Topics: Public Health, Ecology

Buying options

USD 129.00
Price excludes VAT (USA)
  • ISBN: 978-3-030-83160-8
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Hardcover Book
USD 169.99
Price excludes VAT (USA)