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Enzyme Cascade Design and Modelling

  • Creates the basis for pathway design via the concept of ‘biocatalytic retrosynthesis’

  • Enhances the readers’ understanding on kinetic modelling and reaction engineering

  • Introduces process design, process modelling, monitoring and control of catalytic cascades

  • Discusses both multi-enzymatic and chemo-enzymatic cascades

  • Provides an outlook on industrial applications and future developments

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eBook USD 129.00
Price excludes VAT (USA)
  • ISBN: 978-3-030-65718-5
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 169.00
Price excludes VAT (USA)
Hardcover Book USD 169.99
Price excludes VAT (USA)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-vii
  2. Introduction

    • Selin Kara, Florian Rudroff
    Pages 1-6
  3. Enzyme Cascade Design: Retrosynthesis Approach

    • William Finnigan, Sabine L. Flitsch, Lorna J. Hepworth, Nicholas J. Turner
    Pages 7-30
  4. Multi-Enzymatic Cascades In Vitro

    • Sandy Schmidt, Anett Schallmey, Robert Kourist
    Pages 31-48
  5. Multi-Enzymatic Cascades In Vivo

    • Lydia Suchy, Florian Rudroff
    Pages 49-63
  6. Enzyme Cascade Kinetic Modelling

    • Martina Sudar, Zvjezdana Findrik Blažević
    Pages 91-108
  7. Enzyme Cascade Reaction Engineering

    • Philipp Petermeier, Selin Kara
    Pages 109-124
  8. Enzyme Cascade Process Design and Modelling

    • John M. Woodley
    Pages 125-139
  9. Enzyme Cascade Reaction Monitoring and Control

    • Robert Hiessl, Joscha Kleber, Andreas Liese
    Pages 141-163
  10. Enzymatic Cascade Reactions in Non-Conventional Media

    • Javier González-Sabín
    Pages 165-178
  11. Perspectives

    • Selin Kara, Florian Rudroff
    Pages 179-181

About this book

This book provides a comprehensive overview of the recent developments achieved in the field of chemo/enzymatic cascades with topics spanning from design (in vitro and in vivo) to kinetic- and process modelling as well as process control. Opportunities and challenges of building multi-step chemo/enzymatic reactions are discussed, whereby the latter are critically assessed in each chapter and methods to ease the implementation are explored. Both, multi-enzymatic cascades and chemo-enzymatic cascades are presented with the motivation of combining the strengths of these two worlds (e.g. selectivity, activity and robustness) not neglecting the obstacles and challenges of such endeavour. Furthermore, the use of non-conventional media for catalytic cascade reactions, recent achievements and potential for future developments in a technical environment are addressed.

Keywords

  • metabolic engineering
  • industrial biotechnology
  • rational design
  • enzyme pathway
  • multi-enzymatic cascades
  • chemo-enzymatic cascade
  • biochemical engineering

Editors and Affiliations

  • Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark

    Selin Kara

  • Institute of Applied Synthetic Chemistry, TU Wien, Vienna, Austria

    Florian Rudroff

About the editors

Prof. Dr. Selin Kara, Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark

Assoc. Prof. Dr. Florian Rudroff, Institute of Applied Synthetic Chemistry, Vienna University of Technology, Vienna, Austria   


Bibliographic Information

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • ISBN: 978-3-030-65718-5
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 169.00
Price excludes VAT (USA)
Hardcover Book USD 169.99
Price excludes VAT (USA)