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Peritoneal Tumors and Metastases

Surgical, intraperitoneal and systemic therapy

  • Presents a broad overview of peritoneal surface malignancies

  • Provides structured and detailed information on the differential diagnosis and treatment of primary and secondary disease of the peritoneum

  • Selected treatments and procedures are also demonstrated in online videos

  • 21k Accesses

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Table of contents (46 chapters)

  1. Front Matter

    Pages i-xix
  2. Basics

    1. Front Matter

      Pages 1-1
    2. Anatomy and Pathology of the Peritoneum

      • Wiebke Solass, Annette Staebler, Falko Fend, Hans Bösmüller
      Pages 3-22
    3. Pharmacovigilance of Local Chemotherapy in the Peritoneum

      • Susen Burock, Pankaj Kumar Garg, Marc A. Reymond, Alfred Königsrainer
      Pages 23-32
  3. Diagnostic and Natural Course

    1. Front Matter

      Pages 33-33
    2. Diagnostic Imaging of Peritoneal Tumors

      • Bernhard Daniel Klumpp, Christina Pfannenberg
      Pages 35-42
    3. Scoring Systems for CRS and HIPEC

      • Jörg Pelz, Pankaj Kumar Garg
      Pages 49-54
    4. The Natural Course of Peritoneal Carcinomatosis (PC)

      • Jürgen Tepel, Dieudonne Ajah
      Pages 55-58
  4. Treatment Option of Systemic Disease

    1. Front Matter

      Pages 59-59
  5. Treatment Options of Cytoreductive Surgery

    1. Front Matter

      Pages 79-79
    2. Procedures of the Visceral and Parietal Peritonectomy in the Lower Abdomen

      • Philipp Horvath, Alfred Königsrainer, Ingmar Königsrainer
      Pages 89-92
    3. Parietal and Visceral Peritonectomy

      • Beate Rau, Wieland Raue, Pankaj Kumar Garg
      Pages 93-100
    4. Cytoreduction Preparation Devices

      • Horst Günter Rau, Peter Busch, Pankaj Kumar Garg, Igor Yakubov
      Pages 101-108
  6. Treatment Option of Intraperitoneal Treatment and Experimental Approach

    1. Front Matter

      Pages 109-109
    2. Application of IPC, HIPEC, and PIPAC

      • Kurt Van der Speeten, Maik Kilian, Lieselotte Lemione
      Pages 111-133
    3. Cytokine-Induced Senescence: An Experimental Treatment of Peritoneal Tumors

      • Thomas Wieder, Ellen Brenner, Heidi Braumüller, Pankaj Kumar Garg, Martin Röcken
      Pages 135-140

About this book

This book provides surgeons and oncologists with a well-founded and detailed overview of the available treatment options for peritoneal malignancy and differential selection of the appropriate forms of therapy. Systemic chemotherapy options are also considered, as are surgical cytoreduction (CRS) and all forms of intraperitoneal chemotherapy (IPC) especially hyperthermic IPC (HIPEC), and immunotherapy, including specific procedures such as PIPAC.

Subsequent chapters address perioperative care, complications and recurrences, as well as psycho-oncological, palliative medical and nursing care. The process of parietal and visceral peritonectomy in the large and small intestine is additionally illustrated by three video clips accessible online. Covering a broad range of aspects, including peritoneal metastasis and intraperitoneal chemotherapy, the book offers a valuable tool for surgeons, oncologists and anesthesiologists alike.


Keywords

  • Peritoneal carcinomatosis
  • dissiminated disease
  • intraperitoneal chemotherapy
  • Quality of Life
  • Guideline creation
  • rehabilitation psychology

Editors and Affiliations

  • Department of Surgery, Charité – Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität of Berlin, Berlin, Germany

    Beate Rau

  • Department of General, Visceral and Transplant Surgery, University Hospital of Tübingen, Comprehensive Cancer Center, Tübingen, Germany

    Alfred Königsrainer

  • Basingstoke and North Hampshire Hospital, Peritoneal Malignancy Institute, Basingstoke, UK

    Faheez Mohamed

  • Center for Gastrointestinal Malignancies, MedStar Washington Hospital Center, Washington, DC, USA

    Paul H. Sugarbaker

About the editors

Beate Rau is graduated in Medicine and Surgery at the University of Muenster in 1984 and is since 2016 Professor of Surgery at the CHARITÈ Medical University in Berlin. She has specialized in surgical oncology, especially in upper and lower GI-tract- and thoracic-cancer-surgery. Her main interest is surgical oncology, what she mostly did the last 28 years. Beate Rau started her academic carrier in Heidelberg Rohrbach, University of Heidelberg and at the Charité in Berlin. She is very much involved in education of the students and young trainees

Since 2015 she is the head of the Section Special Surgical Oncology at the Charité. Her major interest is hyperthermia which has been central to her career in the field of surgical oncology and research. Convinced by hyperthermia she achieved experience in cytoreductive surgery (CRS) for peritoneal surface malignancies (PSM) and HIPEC over the last 22 years. With her effort, she build up a centre of reference for surgical treatment of PSM in Germany, announced by the German society of general surgery (DGAV) and is therefore responsible for one of the three centres of reference in Germany. She is co-author of several papers (www.scopus.com, www.pubmed.com) with an H-index of 26 (July 2020), wrote one book about peritoneal metastasis and several book-chapters and contributed to many abstracts presented at international and national meetings. She published more than 150 articles.

Alfred Königsrainer completed his medical training at the University of Innsbruck, Austria and has been Chair and Director of the Department of General, Visceral and Transplant Surgery at the University Hospital and Medical Faculty, University of Tübingen, Germany since 2004. After fellowships in Belgium, Germany, Italy and England he was appointed as consultant and vice chairman of the Department of Surgery and Transplantation, University Hospital Innsbruck. He is Chair of the German working group for surgical endoscopy (CAES), past chair of the German Association for the Study of the Liver, past chair of the Austrian society of transplantation, past board member of the European Liver and Intestine Transplantation Association (ELITA), and a Fellow of the American College of Surgery (FACS). With more than 500 publications in scientific journals to his credit, his main focus is on surgical oncology, especially HBP surgery and cytoreductive surgery, HIPEC, PIPAC, and organ transplantation.

Faheez Mohamed graduated from the University of Edinburgh and underwent surgical training in the North East of England with a period of research at the Washington Cancer Institute, USA under the supervision of Dr Paul Sugarbaker. He was appointed Consultant Surgeon at the Peritoneal Malignancy Institute, Basingstoke in 2009 with an interest in cytoreductive surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for the treatment of peritoneal malignancy. He is currently Clinical Director of the Department of General Surgery at Hampshire Hospitals Foundation Trust and is the Clinical Lead for the UK Colorectal Peritoneal Malignancy Clinical Database. He is actively involved in clinical and basic science research in the field of peritoneal malignancy.

Paul Sugarbaker is a graduate of Cornell University Medical College in New York City. His surgical training was at the Peter Bent Brigham Hospital in Boston, Massachusetts. Immediately following his residency training he completed a Masters Degree in Tumor Immunology from Harvard University. From Boston he went to Bethesda, Maryland and spent a decade at the Surgery Branch, National Cancer Institute, National Institutes of Health (NIH). His focus at the NIH was sarcoma surgery, colorectal and liver metastases, and peritoneal metastases. After a brief 3 year stay at the Emory Clinic in Atlanta, Georgia, he returned to Washington, DC to establish the Program in Peritoneal Surface Malignancy at the Washington Cancer Institute. For 31 years he has been involved in pharmacologic and clinical research in patients with peritoneal metastases. His efforts and the efforts of the fellows in the program have resulted in over a thousand published manuscripts. Currently, he is involved in surgical problem solving in an effort to optimize the management of peritoneal metastases from both gynecologic and gastrointestinal malignancy. He is currently the Secretary General for the Peritoneal Surface Oncology Group International (PSOGI).  

Bibliographic Information

  • Book Title: Peritoneal Tumors and Metastases

  • Book Subtitle: Surgical, intraperitoneal and systemic therapy

  • Editors: Beate Rau, Alfred Königsrainer, Faheez Mohamed, Paul H. Sugarbaker

  • DOI: https://doi.org/10.1007/978-3-030-62640-2

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2021

  • Hardcover ISBN: 978-3-030-62639-6Published: 14 May 2021

  • Softcover ISBN: 978-3-030-62642-6Published: 14 May 2022

  • eBook ISBN: 978-3-030-62640-2Published: 13 May 2021

  • Edition Number: 1

  • Number of Pages: XIX, 407

  • Number of Illustrations: 20 b/w illustrations, 70 illustrations in colour

  • Topics: Surgery, Oncology, Anesthesiology, Rehabilitation Medicine

Buy it now

Buying options

eBook USD 119.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 159.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access