Skip to main content
  • Book
  • © 2021

Cannabinoids and Sleep

Molecular, Functional and Clinical Aspects

  • Offers a comprehensive overview on cannabinoids and their effects on sleep

  • Provides novel research findings on the therapeutic potential of cannabinoids

  • Discusses the effect of cannabinoids in several neurological disorders

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1297)

Buy it now

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (14 chapters)

  1. Front Matter

    Pages i-xxii
  2. Constituents of Cannabis sativa

    • Carolina Echeverry, Miguel Reyes-Parada, Cecilia Scorza
    Pages 1-9
  3. Synthetic and Natural Derivatives of Cannabidiol

    • Paula Morales, Nadine Jagerovic
    Pages 11-25
  4. Clinical Pharmacokinetics of Cannabinoids and Potential Drug-Drug Interactions

    • Marta Vázquez, Carlos García-Carnelli, Cecilia Maldonado, Pietro Fagiolino
    Pages 27-42
  5. Cannabinoid Receptors and Ligands: Lessons from CNS Disorders and the Quest for Novel Treatment Venues

    • Clara M. Vecchini Rodríguez, Yma Escalona Meléndez, Jacqueline Flores-Otero
    Pages 43-64
  6. Sleep-Wake Neurobiology

    • Giancarlo Vanini, Pablo Torterolo
    Pages 65-82
  7. Cannabinoids and Sleep/Wake Control

    • Mónica Méndez-Díaz, Alejandra E. Ruiz-Contreras, Jacqueline Cortés-Morelos, Oscar Prospéro-García
    Pages 83-95
  8. Effects of Cannabinoid Agonists and Antagonists on Sleep in Laboratory Animals

    • Maureen L. Petrunich-Rutherford, Michael W. Calik
    Pages 97-109
  9. Natural Cannabinoids as Templates for Sleep Disturbances Treatments

    • Eric Murillo-Rodríguez, Sérgio Machado, Claudio Imperatori, Tetsuya Yamamoto, Henning Budde
    Pages 133-141
  10. Effects of Cannabis Consumption on Sleep

    • Alejandra Mondino, Matías Cavelli, Joaquín González, Eric Murillo-Rodriguez, Pablo Torterolo, Atilio Falconi
    Pages 147-162
  11. Addiction and Sleep Disorders

    • Jonathan Ek, William Jacobs, Brett Kaylor, W. Vaughn McCall
    Pages 163-171
  12. Cannabis for Restless Legs Syndrome

    • Imad Ghorayeb
    Pages 173-181

About this book

Research on cannabis and sleep is emerging with promising results. This book offers current and comprehensive knowledge on cannabinoid research results in connection with sleep. The volume covers aspects of the hemp plant Cannabis sativa, the pharmacology of cannabinoids, neurobiology and pharmacology of sleep and wakefulness, and the benefits and side effects of cannabis on the central nervous system. It further discusses the putative therapeutical properties of cannabinoids and endocannabinoids and their potential for the treatment of sleep disorders such as insomnia, obstructive sleep apnea, REM sleep behavior disorder, and restless legs syndrome.

The book is written by medical and scientific experts in this field and intended for researchers from a range of disciplines such as biomedicine, biology, neurosciences, clinical medicine, neurology, and pharmacology.


Editors and Affiliations

  • School of Medicine, University of the Republic, Montevideo, Uruguay

    Jaime M. Monti

  • Somnogen Canada Inc., Toronto, Canada

    S. R. Pandi-Perumal

  • División Ciencias de la Salud, Universidad Anáhuac Mayab, Merida, Mexico

    Eric Murillo-Rodríguez

About the editors

Jaime Monti, MD, is associated with the University of the Republic, Uruguay. He has completed post-doctoral studies at the National Institute of Health, USA.  He is full Professor of Pharmacology and Therapeutic and the School of Medicine of the Republic University, Professor of the Basic Sciences Development Program (PEDECIBA) and Researcher the National Researchers' System. He is a globally recognized sleep researcher and has been awarded with the prestigious Claude Bernard Prize (French Governemnt) and with the Schering Award for Basic Sleep Research (USA).  He is an international recognized expert in the neuropharmacology of sleep and wakefulness, with more than two hundred publications in this field.  

S. R. Pandi-Perumal, MSc, is the President and Chief Executive Officer of Somnogen Canada Inc, a Canadian Corporation. He is a well-recognized sleep researcher, both nationally and internationally, and has authored over 200 publications. His general area of research interest includes sleep and biological rhythms. He is a well-known editor in the field of sleep medicine and has edited over 25 volumes dealing with various sleep-related topics. He received an honorable mention in the New York Times in 2004. The India International Friendship Society awarded him the prestigious Bharat Gaurav award on January 12, 2013. The Bharat Gaurav Award is usually recognition of a person who has made achievements in a particular field, which in turn will put a positive impact on the society at large. 

Dr. Eric Murillo-Rodríguez is Psychologist and holds a PhD. in Biomedical Sciences, both degrees obtained by the National Autonomous University of Mexico (UNAM). Upon graduation, he completed his postdoctoral training at Harvard Medical School. His scientific contribution includes over 70 peer-reviewed publications in various reputed scientific and medical journals, 10 chapters in books. He is an active member of several scientific societies and the editorial board members of various journals.Dr. Murillo-Rodríguez has received outstanding academic achievements such as “Young Investigator Award” given by the World Federation of Sleep Research Societies (WFSRS) in 2003, and subsequently the “Young Investigator Honorable Mention” awarded by the Sleep Research Society (SRS) in 2004.   

Bibliographic Information

  • Book Title: Cannabinoids and Sleep

  • Book Subtitle: Molecular, Functional and Clinical Aspects

  • Editors: Jaime M. Monti, S. R. Pandi-Perumal, Eric Murillo-Rodríguez

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-030-61663-2

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Switzerland AG 2021

  • Hardcover ISBN: 978-3-030-61662-5Published: 04 February 2021

  • Softcover ISBN: 978-3-030-61665-6Published: 04 February 2022

  • eBook ISBN: 978-3-030-61663-2Published: 03 February 2021

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XXII, 183

  • Number of Illustrations: 16 b/w illustrations, 21 illustrations in colour

  • Topics: Molecular Medicine, Neurosciences

Buy it now

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access