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  • Book
  • Jan 2021

Optical Whispering Gallery Modes for Biosensing

From Physical Principles to Applications

  • Explains the fundamentals of optical whispering gallery modes at a level understandable to graduate students

  • Appeals to an interdisciplinary readership comprised of physicists, bioengineers, and medical professionals

  • Discusses advanced applications of whispering gallery modes for exploring the fundamentals of quantum physics

Part of the book series: Biological and Medical Physics, Biomedical Engineering (BIOMEDICAL)

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Table of contents (7 chapters)

  1. Front Matter

    Pages i-xiii
  2. Sensing with Light

    • Frank Vollmer, Deshui Yu
    Pages 1-59
  3. Surface Plasmon Resonance

    • Frank Vollmer, Deshui Yu
    Pages 61-115
  4. Whispering Gallery Modes in Optical Microcavities

    • Frank Vollmer, Deshui Yu
    Pages 117-170
  5. Applications of WGM Microcavities in Physics

    • Frank Vollmer, Deshui Yu
    Pages 171-232
  6. Single-Molecule Sensing

    • Frank Vollmer, Deshui Yu
    Pages 233-298
  7. Fundamentals of Quantum Optics

    • Frank Vollmer, Deshui Yu
    Pages 299-344
  8. Molecular Cavity QED

    • Frank Vollmer, Deshui Yu
    Pages 345-383
  9. Back Matter

    Pages 385-416

About this book

This interdisciplinary book covers the fundamentals of optical whispering gallery mode (WGM) microcavities, light–matter interaction, and biomolecular structure with a focus on applications in biosensing. Novel biosensors based on the hybridization of WGM microcavities and localized surface plasmon resonances (LSPRs) in metal nanoparticles have emerged as the most sensitive microsystem biodetection technology that boasts single molecule detection capability without the need for amplification and labeling of the analyte. The book provides an ample survey of the physical mechanisms of WGMs and LSPRs for detecting affinity, concentration, size, shape and orientation of biomarkers, while informing the reader about different classes of biomolecules, their optical properties and their importance in label-free clinical diagnostics. For the more advanced reader, advanced applications of WGMs and LSPRs in exploring the fundamental nature of quantum physics are discussed.



  • Localized Surface Plasmon Resonances
  • Biomedical Diagnostics Book
  • Biomolecular Interactions
  • Biosensing for Clinical Diagnostics
  • Integrated Photonics
  • Microresonators
  • Microsystem Biodetection Technology
  • Optical Resonators

Authors and Affiliations

  • Physics and Astronomy, University of Exeter, Exeter, UK

    Frank Vollmer, Deshui Yu

Bibliographic Information