© 2020

Management of Hereditary Colorectal Cancer

A Multidisciplinary Approach

  • Jose G. Guillem
  • Garrett Friedman

Table of contents

  1. Front Matter
    Pages i-xii
  2. Aung K. Win, Garrett Friedman, Jose G. Guillem
    Pages 1-9
  3. Peter C. Ambe, Gabriela Möslein
    Pages 11-39
  4. Chady Atallah, Francis M. Giardiello, Jonathan Efron
    Pages 41-59
  5. Robert Gryfe, Rory Kennelly
    Pages 61-80
  6. Jennifer K. Maratt, Elena M. Stoffel
    Pages 81-101
  7. Susan K. Clark
    Pages 103-122
  8. Coen L. Klos, Farhan Quader, Dayna Early, Paul E. Wise
    Pages 137-147
  9. William C. Cirocco, Heather Hampel
    Pages 149-174
  10. Y. Nancy You, Marcelli Marcante, Thomas J. George Jr.
    Pages 175-200
  11. Back Matter
    Pages 201-207

About this book


This book provides a comprehensive review of the clinical management of hereditary colorectal cancer. The text focuses on six distinct patient groups: patients with early age-of-onset colorectal cancer and adenomas, patients with hamartomatous colorectal polyps, patients afflicted with familial adenomatous polyposis (FAP), patients with attenuated familial adenomatous polyposis (AFAP), patients with MYH associated polyposis (MAP), and patients afflicted with lynch syndrome (LS). Each chapter illustrates how clinicians utilize current technologies in genetic testing, pathological review, and endoscopic, surgical, and chemotherapeutic/immunotherapeutic approaches to manage these patient groups. Topics such as the timing of genetic testing, endoscopic screening and surveillance, prophylactic surgical options and chemo-preventive interventions are also discussed in concise yet precise detail. 

Written by experts in their fields, Management of Hereditary Colorectal Cancer: A Multidisciplinary Approach is a valuable and timely resource for gastroenterologists, surgeons, genetic counselors, medical oncologists, psychologists, and any health caregivers involved with the management of patients and families afflicted with a hereditary form of colorectal cancer.


JPS PJS familial adenomatous polyposis attenuated FAP MYH associated Polyposis lynch syndrome

Editors and affiliations

  • Jose G. Guillem
    • 1
  • Garrett Friedman
    • 2
  1. 1.Gastrointestinal Surgery, University of North CarolinaChapel HillUSA
  2. 2.Department of SurgeryMike O’Callaghan Federal Medical CenterLas VegasUSA

About the editors

Jose G. Guillem, MD, MPH
Memorial Sloan Kettering Cancer Center
Cornell University Medical College
New York, NY 

Maj. Garrett Friedman, MD
Nellis Air Force Base
Las Vegas, NV

Bibliographic information

  • Book Title Management of Hereditary Colorectal Cancer
  • Book Subtitle A Multidisciplinary Approach
  • Editors Jose G. Guillem
    Garrett Friedman
  • DOI
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Softcover ISBN 978-3-030-26233-4
  • eBook ISBN 978-3-030-26234-1
  • Edition Number 1
  • Number of Pages XII, 207
  • Number of Illustrations 6 b/w illustrations, 12 illustrations in colour
  • Topics Gastroenterology
  • Buy this book on publisher's site


“This book has a broad target audience including both medical and surgical providers. … This is a very focused book on the treatment of a relatively rare population. The information is well presented. Each chapter is clear and concise and addresses an important aspect of the care of these patients. This will be a valuable resource for individuals who manage hereditary colorectal cancer.” (Peter Nau, Doody's Book Reviews, July 17, 2020)